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Engineered spider silk protein-based composites for drug delivery

Title data

Hardy, John G. ; Leal-Egaña, Aldo ; Scheibel, Thomas:
Engineered spider silk protein-based composites for drug delivery.
In: Macromolecular Bioscience. Vol. 13 (October 2013) Issue 10 . - pp. 1431-1437.
ISSN 1616-5187
DOI: https://doi.org/10.1002/mabi.201300233

Official URL: Volltext

Abstract in another language

Silk protein-based materials are promising materials for the delivery of drugs and other active ingredients, due to their processability, biocompatibility, and biodegradability. The preparation of films composed of an engineered spider silk protein (eADF4(C16)) in combination with either a polyester (polycaprolactone) or a polyurethane (pellethane), and their physical properties are described. The release profiles are affected by both the film composition and the presence of enzymes, and release can be observed over a period of several weeks. Such silk-based composites have potential as drug eluting biocompatible coatings or implantable devices.

Further data

Item Type: Article in a journal
Refereed: Yes
Additional notes: Der Artikel wurde zunächst online veröffentlicht am 23.07.2013
Keywords: biodegradable biomaterials; coatings; composites; drug delivery
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Emerging Fields > Food and Health Sciences
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Emerging Fields
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 21 Apr 2015 06:38
Last Modified: 28 Sep 2018 07:35
URI: https://eref.uni-bayreuth.de/id/eprint/10574