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A novel biosensor platform for inflammation analysis : assessment of platform feasibility


Metzner, Julia ; Luckert, Katrin ; Moos, Ralf ; Hämmerle, Martin:
A novel biosensor platform for inflammation analysis : assessment of platform feasibility.
Veranstaltung: 1st European & 10th German BioSensor Symposium , 20.3.-23.3.2017 , Potsdam.
(Veranstaltungsbeitrag: Kongress/Konferenz/Symposium/Tagung , Poster )


Biosensors are - amongst others - suitable for applications in medicine, environmental analysis, food monitoring, and industrial processes due to their miniaturization potential and their specific detection principles. For medical purposes, different commercial biosensors are available on the market. Furthermore, several sensor platforms are described in the scientific literature. Antibody-based biosensor platforms, for example, offer the opportunity to diagnose the inflammatory status. Hence, aim of this work is to develop an electrochemical immunosensor platform for inflammation analysis allowing for protein detection in the lower concentration range (pg/ml). Furthermore, an innovative measurement scenario is proposed to address analysis challenges such as parallelization or time-consuming workflows of standard techniques, such as enzyme-linked immunosorbent assays (ELISA). Here, results are shown for the investigation of different sensor concepts for the detection of IL-13 as model analyte. All the different sensor concepts comprise the same electrochemical detection principle, but are based on different electrode materials or support materials onto which the capture antibodies are immobilized.

Weitere Angaben

Publikationsform: Veranstaltungsbeitrag (Poster)
Begutachteter Beitrag: Ja
Institutionen der Universität: Fakultäten > Fakultät für Ingenieurwissenschaften
Fakultäten > Fakultät für Ingenieurwissenschaften > Lehrstuhl Funktionsmaterialien > Lehrstuhl Funktionsmaterialien - Univ.-Prof. Dr.-Ing. Ralf Moos
Profilfelder > Advanced Fields > Neue Materialien
Forschungseinrichtungen > Forschungszentren > Bayreuther Materialzentrum - BayMAT
Fakultäten > Fakultät für Ingenieurwissenschaften > Lehrstuhl Funktionsmaterialien
Profilfelder > Advanced Fields
Forschungseinrichtungen > Forschungszentren
Titel an der UBT entstanden: Ja
Themengebiete aus DDC: 600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften
Eingestellt am: 03 Apr 2017 08:04
Letzte Änderung: 03 Apr 2017 08:04
URI: https://eref.uni-bayreuth.de/id/eprint/36735