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Stroganov, Vladislav ; Zakharchenko, Svetlana ; Sperling, Evgeni ; Meyer, Anne K. ; Schmidt, Oliver G. ; Ionov, Leonid:
Biodegradable Self-Folding Polymer Films with Controlled Thermo-Triggered Folding.
In: Advanced Functional Materials.
Bd. 24
(2014)
Heft 27
.
- S. 4357-4363.
ISSN 1616-3028
DOI: https://doi.org/10.1002/adfm.201400176
Abstract
Self-folding films are a unique kind of thin film. They are able to deform in response to a change in environmental conditions or internal stress and form complex 3D structures. They are very promising candidates for the design of bioscaffolds, which resemble different kinds of biological tissues. In this paper, a very simple and cheap approach for the fabrication of fully biodegradable and biocompatible self-rolled tubes is reported. The tubes' folding can be triggered by temperature. A bilayer approach is used, where one component is active and another one is passive. The passive one can be any biocompatible, biodegradable, hydrophobic polymer. Gelatin is used as an active component: it allows the design of (i) self-folding polymer films, which fold at room temperature (22 °C) and irreversibly unfold at 37 °C, and (ii) films, which are unfolded at room temperature (22 °C), but irreversibly fold at 37 °C. The possibilities of encapsulation of neural stem cells are also demonstrated using self-folded tubes.
Weitere Angaben
| Publikationsform: | Artikel in einer Zeitschrift |
|---|---|
| Begutachteter Beitrag: | Ja |
| Keywords: | polymers; hydrogels; thermoresponsive; actuators; biodegradable; thin films; biocompatible |
| Institutionen der Universität: | Fakultäten Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Biologie Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Biologie > Lehrstuhl Ökologische Mikrobiologie Fakultäten > Fakultät für Ingenieurwissenschaften Fakultäten > Fakultät für Ingenieurwissenschaften > Professur Biofabrikation Fakultäten > Fakultät für Ingenieurwissenschaften > Professur Biofabrikation > Professur Biofabrikation - Univ.-Prof. Dr. Leonid Ionov |
| Titel an der UBT entstanden: | Ja |
| Themengebiete aus DDC: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
| Eingestellt am: | 19 Jun 2017 13:25 |
| Letzte Änderung: | 10 Mär 2022 10:08 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/37680 |