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Biodegradable Self-Folding Polymer Films with Controlled Thermo-Triggered Folding

Title data

Stroganov, Vladislav ; Zakharchenko, Svetlana ; Sperling, Evgeni ; Meyer, Anne K. ; Schmidt, Oliver G. ; Ionov, Leonid:
Biodegradable Self-Folding Polymer Films with Controlled Thermo-Triggered Folding.
In: Advanced Functional Materials. Vol. 24 (16 July 2014) Issue 27 . - pp. 4357-4363.
ISSN 1616-301X
DOI: https://doi.org/10.1002/adfm.201400176

Abstract in another language

Self-folding films are a unique kind of thin film. They are able to deform in response to a change in environmental conditions or internal stress and form complex 3D structures. They are very promising candidates for the design of bioscaffolds, which resemble different kinds of biological tissues. In this paper, a very simple and cheap approach for the fabrication of fully biodegradable and biocompatible self-rolled tubes is reported. The tubes' folding can be triggered by temperature. A bilayer approach is used, where one component is active and another one is passive. The passive one can be any biocompatible, biodegradable, hydrophobic polymer. Gelatin is used as an active component: it allows the design of (i) self-folding polymer films, which fold at room temperature (22 °C) and irreversibly unfold at 37 °C, and (ii) films, which are unfolded at room temperature (22 °C), but irreversibly fold at 37 °C. The possibilities of encapsulation of neural stem cells are also demonstrated using self-folded tubes.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: polymers; hydrogels; thermoresponsive; actuators; biodegradable; thin films; biocompatible
Institutions of the University: Faculties > Faculty of Engineering Science > Professur Biofabrikation > Professur Biofabrikation - Univ.-Prof. Dr. Leonid Ionov
Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Professur Biofabrikation
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 19 Jun 2017 13:25
Last Modified: 20 Jun 2017 08:12
URI: https://eref.uni-bayreuth.de/id/eprint/37680