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MPS and MRI efficacy of magnetosomes from wild-type and mutant bacterial strains

Title data

Heinke, David ; Kraupner, Alexander ; Eberbeck, Dietmar ; Schmidt, Daniel ; Radon, Patricia ; Uebe, René ; Schüler, Dirk ; Briel, Andreas:
MPS and MRI efficacy of magnetosomes from wild-type and mutant bacterial strains.
In: International Journal on Magnetic Particle Imaging. Vol. 3 (22 June 2017) Issue 2 . - pp. 1-6.

Official URL: Volltext

Abstract in another language

The future of Magnetic Particle Imaging (MPI), as a tracer-based imaging modality, crucially relies on the development of high-performing tracers. Due to their ideal structural and magnetic properties, biogenic nanoparticles extracted from magnetotactic bacteria are promising candidates for MPI tracer research. In the present study we investigate the potential of bacterial magnetosomes, extracted from wild-type bacteria of the strain Magnetospirillum gryphiswaldense and various mutants thereof, as new tracer materials for MPI. Furthermore, we investigate the structural and magnetic properties of the magnetosomes as well as their suitability as Magnetic Resonance Imaging (MRI) agents in order to explain differences in MPI and MRI efficacies.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: MPI tracer research; magnetosomes; MPS; MRI agent
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Microbiology
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Microbiology > Chair Microbiology - Univ.-Prof. Dr. Dirk Schüler
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology
Result of work at the UBT: No
DDC Subjects: 500 Science
500 Science > 570 Life sciences, biology
Date Deposited: 07 Sep 2017 14:19
Last Modified: 09 Apr 2019 07:29
URI: https://eref.uni-bayreuth.de/id/eprint/39385