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Monodisperse collagen-gelatin beads as potential platforms for 3D cell culturing

Title data

Ma, Shaohua ; Natoli, Manuela ; Liu, Xin ; Neubauer, Martin Peter ; Watt, Fiona M. ; Fery, Andreas ; Huck, Wilhelm T. S.:
Monodisperse collagen-gelatin beads as potential platforms for 3D cell culturing.
In: Journal of Materials Chemistry B. Vol. 1 (2013) Issue 38 . - pp. 5128-5136.
ISSN 2050-7518
DOI: https://doi.org/10.1039/C3TB20851F

Official URL: Volltext

Abstract in another language

A droplet-based microfluidics technique is used to produce monodisperse, 80 mm collagen--gelatin beads with tunable mechanical properties in the range of 1--10 kPa after photo-crosslinking. The gel beads are porous, mechanically robust and stable in buffer, but can be degraded enzymatically. Encapsulated fibroblast cells maintain 70 viability after one-week encapsulation and preliminary results show that the degree of spreading of cells in gels is correlated with the stiffness of the material.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors > Chair Physical Chemistry II - Univ.-Prof. Dr. Andreas Fery
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Physical Chemistry II
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 500 Natural sciences
500 Science > 530 Physics
500 Science > 540 Chemistry
Date Deposited: 05 Dec 2014 07:44
Last Modified: 12 Feb 2019 09:50
URI: https://eref.uni-bayreuth.de/id/eprint/3940