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Structures of Human Peptide Hormones in Solution

Title data

Marx, Ute C. ; Adermann, Knut ; Schulz, Axel ; Meyer, Markus ; Forssmann, Wolf-Georg ; Rösch, Paul:
Structures of Human Peptide Hormones in Solution.
In: Jardetzky, Oleg (ed.): Dynamics, structure and function of biological macromolecules. - Amsterdam : IOS Press , 2001 . - pp. 145-161 . - (NATO ASI Series : Series A, Life sciences ; 315 )
ISBN 1-58603-032-9

Abstract in another language

Human peptide hormones are components of various regulation mechanisms. Parathyroid hormone (PTH), for example, is involved in calcium homeostasis in blood and, additionally, plays a crucial role in bone metabolism. Uroguanylin is part of the intestinal epithelial electrolyte regulation machinery acting via the guanylyl cyclase pathway.

Structure determination of peptide hormones is an important step to coorelate structure and function, to understand endocrine diseases on a molecular level, and to design therapeutics mimicking the peptide structure.

Further data

Item Type: Article in a book
Refereed: Yes
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors > Chair Biopolymers - Univ.-Prof. Dr. Paul Rösch
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biopolymers
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
500 Science > 570 Life sciences, biology
Date Deposited: 24 Jan 2019 07:57
Last Modified: 06 Jun 2019 13:09
URI: https://eref.uni-bayreuth.de/id/eprint/47012