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Engineering of silk proteins for materials applications

Title data

Saric, Merisa ; Scheibel, Thomas:
Engineering of silk proteins for materials applications.
In: Current Opinion in Biotechnology. Vol. 60 (December 2019) . - pp. 213-220.
ISSN 1879-0429
DOI: https://doi.org/10.1016/j.copbio.2019.05.005

Abstract in another language

Silk combines biological properties, such as non-toxicity and biodegradability, with physico-chemical ones, for example, mechanical strength. Base on molecular engineering, nowadays also new non-silk functions can be implemented in silk materials. Driven by rational design and ingenuity, innovative recombinant silk proteins can be designed with a plethora of functions to address biomedical and technological challenges. Herein, we review advances in engineering silk proteins for tailored functions at the molecular level. Insights are provided in genetically engineered silk fusions with functional or other structural proteins and in hybrids with DNA. In such novel materials, self-assembly features of silk are combined and utilized with expedient properties of the additional components. The availability of functionalized silk materials is opening routes toward a whole set of novel applications not achievable with natural silk or other polymers

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Emerging Fields
Profile Fields > Emerging Fields > Food and Health Sciences
Research Institutions
Research Institutions > Research Centres
Research Institutions > Research Centres > Bayreuth Center for Material Science and Engineering - BayMAT
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 20 Jan 2020 12:02
Last Modified: 20 Jan 2020 12:02
URI: https://eref.uni-bayreuth.de/id/eprint/54146