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Nanostructured, Self-Assembled Spider Silk Materials for Biomedical Applications

Title data

Humenik, Martin ; Pawar, Kiran ; Scheibel, Thomas:
Nanostructured, Self-Assembled Spider Silk Materials for Biomedical Applications.
In: Perrett, Sarah ; Buell, Alexander K. ; Knowles, Thomas P. J. (ed.): Biological and Bio-inspired Nanomaterials : Properties and Assembly Mechanisms. - Singapore , 2019 . - pp. 187-221 . - (Advances in Experimental Medicine and Biology ; 1174 )
ISBN 978-981-139-791-2
DOI: doi.org/10.1007/978-981-13-9791-2_6

Abstract in another language

The extraordinary mechanical properties of spider silk fibers result from the interplay of composition, structure and self-assembly of spider silk proteins (spidroins). Genetic approaches enabled the biotechnological production of recombinant spidroins which have been employed to unravel the self-assembly and spinning process. Various processing conditions allowed to explore non-natural morphologies including nanofibrils, particles, capsules, hydrogels, films or foams. Recombinant spider silk proteins and materials made thereof can be utilized for biomedical applications, such as drug delivery, tissue engineering or 3D-biomanufacturing.

Further data

Item Type: Article in a book
Refereed: Yes
Keywords: Biofabrication; Drug delivery; Fibers; Genetic engineering; Recombinant production; Self-assembly; Spider silk; Tissue engineering
Institutions of the University: Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Profile Fields
Profile Fields > Advanced Fields
Profile Fields > Advanced Fields > Polymer and Colloid Science
Profile Fields > Advanced Fields > Advanced Materials
Profile Fields > Advanced Fields > Molecular Biosciences
Profile Fields > Emerging Fields
Profile Fields > Emerging Fields > Food and Health Sciences
Research Institutions
Research Institutions > Research Centres
Research Institutions > Research Centres > Bayreuth Center for Material Science and Engineering - BayMAT
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences
600 Technology, medicine, applied sciences > 620 Engineering
Date Deposited: 20 Jan 2020 12:48
Last Modified: 20 Jan 2020 12:48
URI: https://eref.uni-bayreuth.de/id/eprint/54160