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RNA editing : Getting U into RNA

Title data

Kable, Moffett L. ; Heidmann, Stefan ; Stuart, Kenneth D.:
RNA editing : Getting U into RNA.
In: Trends in Biochemical Sciences. Vol. 22 (May 1997) Issue 5 . - pp. 162-166.
ISSN 0968-0004
DOI: https://doi.org/10.1016/S0968-0004(97)01041-4

Abstract in another language

RNA editing in kinetoplastid protozoa remodels the sequences of mitochondrial pre-mRNAs by the precise insertion and deletion of uridylate residues. These sequence changes are directed by small trans-acting RNAs, termed guide RNAs. The basic mechanistic pathway by which edited RNA is generated has recently been elucidated using in vitro systems capable of a full round of guide-RNA-directed editing.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: Messenger-RNA; In-Vitro; Kinetoplastid Mitochondria; GRNA; Molecules; Chimeras; Ligase; Information; Complexes; Proteins
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Genetics
Result of work at the UBT: No
DDC Subjects: 500 Science > 570 Life sciences, biology
Date Deposited: 12 Mar 2020 12:34
Last Modified: 12 Mar 2020 12:34
URI: https://eref.uni-bayreuth.de/id/eprint/54607