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Protein folding as a diffusional process

Title data

Jacob, Maik H. ; Schmid, Franz X.:
Protein folding as a diffusional process.
In: Biochemistry. Vol. 38 (19 October 1999) Issue 42 . - pp. 13773-13779.
ISSN 0006-2960
DOI: https://doi.org/10.1021/bi991503o

Abstract in another language

A protein chain must move relative to the solvent molecules and explore many conformations when it folds from the extended unfolded state to the compact native state. Experimental and theoretical approaches suggest that diffusional processes in fact contribute to the kinetics of protein folding. We describe here how variations of the solvent viscosity can be employed to uncover the diffusional contributions to a folding reaction and assess the use of transition state theory and Kramers' rate theory for the analysis of protein folding reactions.

Further data

Item Type: Article in a journal
Refereed: Yes
Additional notes: PubMed-ID: 10529221
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors > Professorship Biochemistry - Univ.-Prof. Dr. Franz Xaver Schmid
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Professorship Biochemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 28 May 2015 07:06
Last Modified: 28 May 2015 07:06
URI: https://eref.uni-bayreuth.de/id/eprint/14374