bei Google ScholarTitelangaben
Piontek, Christian ; Ring, Petra ; Harjes, Olaf ; Heinlein, Christian ; Mezzato, Stefano ; Lombana Sanchez, Jose Nelson ; Pöhner, Claudia ; Püttner, Markus ; Varón Silva, Daniel ; Martin, Andreas ; Schmid, Franz X. ; Unverzagt, Carlo:
Semisynthesis of a homogeneous glycoprotein enzyme : ribonuclease C: part 1.
In: Angewandte Chemie International Edition.
Bd. 48
(2009)
Heft 11
.
- S. 1936-1940.
ISSN 1521-3773
DOI: https://doi.org/10.1002/anie.200804734
Abstract
Seven in one blow: The efficient formation of mixed disulfides on the thiol-rich fusion protein A followed by subsequent intein cleavage gave the fragment B with all seven cysteines protected against oxidation. The native chemical ligation of B with synthetic glycopeptide thioesters provides glycoproteins.