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Temperature controlled encapsulation and release using partially biodegradable thermo-magneto-sensitive self-rolling tubes

Title data

Zakharchenko, Svetlana ; Puretskiy, Nikolay ; Stoychev, Georgi ; Stamm, Manfred ; Ionov, Leonid:
Temperature controlled encapsulation and release using partially biodegradable thermo-magneto-sensitive self-rolling tubes.
In: Soft Matter. Vol. 6 (2010) Issue 12 . - pp. 2633-2636.
ISSN 1744-6848
DOI: https://doi.org/10.1039/C0SM00088D

Abstract in another language

We suggest a new approach for controlled encapsulation and release of microparticles, cells and drugs using thin bilayer films of thermoresponsive and biodegradable polymers, which are able to form self-rolling tubes. The magnetic nanoparticles are incorporated in the thermoresponsive layer in order to provide the microtubes sensitivity to magnetic field. We demonstrate reversible rolling and unrolling of the polymer films, reversible capture and release of microparticles in response to change of temperature as well as manipulation of particle-loaded microtubes using external magnetic field. The suggested approach can be successfully implemented for controlled delivery of drugs and cells in living organisms as well as to design scaffolds for tissue engineering.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Engineering Science > Professur Biofabrikation > Professur Biofabrikation - Univ.-Prof. Dr. Leonid Ionov
Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Professur Biofabrikation
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 23 Jun 2017 06:09
Last Modified: 23 Jun 2017 06:09
URI: https://eref.uni-bayreuth.de/id/eprint/37859