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Crystalline forms for 5-amino-2, 3-dihydrophthalazine-1, 4-dione sodium salt, pharmaceutical preparations containing the same and method for the production of said forms

Title data

Breu, Josef ; Bensch, Wolfgang ; Kaiser, Astrid ; Ludescher, Beate ; Maass, Gerrit ; Martin, Thomas ; Milius, Wolfgang ; Niedermaier, Michael:
Crystalline forms for 5-amino-2, 3-dihydrophthalazine-1, 4-dione sodium salt, pharmaceutical preparations containing the same and method for the production of said forms.
US8772294B2 (2014)

Abstract in another language

The invention relates to the provision of two novel crystalline forms I and II for 5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt. Surprisingly, it was discovered that form I and form II have differing immunological effects. This advantageous property is useful for immunospecific applications. In addition, both forms have advantageous physicochemical properties, which are useful in the production, further processing and/or use of a pharmaceutical preparation of form I or form II or a mixture of both.

Crystalline forms for 5-amino-2, 3-dihydrophthalazine-1, 4-dione sodium salt, pharmaceutical preparations containing the same and method for the production of said forms (PDF Download Available). Available from: https://www.researchgate.net/publication/302753678_Crystalline_forms_for_5-amino-2_3-dihydrophthalazine-1_4-dione_sodium_salt_pharmaceutical_preparations_containing_the_same_and_method_for_the_production_of_said_forms [accessed Mar 27 2018].

Further data

Item Type: Patent
Date of the patent's registration: July 2014
Institutions of the University: Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Anorganic Chemistry I
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Anorganic Chemistry I > Chair Anorganic Chemistry I - Univ.-Prof. Dr. Josef Breu
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 29 Mar 2018 09:37
Last Modified: 29 Mar 2018 09:37
URI: https://eref.uni-bayreuth.de/id/eprint/43163