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Electronic biosensing with flexible organic transistor devices

Title data

Kotlowski, Caroline ; Aspermair, Patrik ; Khan, Hadayat Ullah ; Reiner-Rozman, Ciril ; Breu, Josef ; Szunerits, Sabine ; Kim, Jang-Joo ; Bao, Zhenan ; Kleber, Christoph ; Pelosi, Paolo ; Knoll, Wolfgang:
Electronic biosensing with flexible organic transistor devices.
In: Flexible and Printed Electronics. Vol. 3 (2018) Issue 3 . - Art.Nr. 034003.
ISSN 2058-8585
DOI: https://doi.org/10.1088/2058-8585/aad433

Project information

Project financing: Andere

Abstract in another language

In this short review, we summarize the design and implementation of organic semiconducting materials-based field-effect transistors (OFETs) and the fabrication and use of reduced graphene-oxide field-effect transistors (rGO-FETs) as flexible transducers for electronic biosensing. We demonstrate that these platforms allow for the quantitative, in situ, and in real time monitoring of bio-affinity reactions between analytes from solution to the surface-immobilized receptors. The examples given include the binding of anti-bovine serum albumin (BSA) antibodies to their antigen, BSA, covalently attached to the channel of an OFET, or the reverse mode of operation, i.e., the binding of BSA from solution to the antibodies immobilized on a rGO transistor. Finally, we will discuss a few results obtained with odorant binding proteins used as receptors on a rGO-FET transducer for the realization of a biomimetic smell sensor.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: electronic biosensing; immunosensing; antigen-antibody interaction; OFET; rGO-FET; biomimetic smell sensing; graphene; films
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Inorganic Chemistry I > Chair Inorganic Chemistry I - Univ.-Prof. Dr. Josef Breu
Result of work at the UBT: No
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 03 Dec 2019 13:30
Last Modified: 03 Dec 2019 13:30
URI: https://eref.uni-bayreuth.de/id/eprint/53457