Titelangaben
Hanefeld, Phillip ; Agarwal, Seema ; Kumar, Rakesh ; Greiner, Andreas:
In Vitro Study of Dexamethasone Release From Poly(p-xylylene) Films.
In: Macromolecular Chemistry and Physics.
Bd. 211
(2010)
Heft 2
.
- S. 265-269.
ISSN 1521-3935
DOI: https://doi.org/10.1002/macp.200900537
Angaben zu Projekten
Projektfinanzierung: |
Deutsche Forschungsgemeinschaft SCS |
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Abstract
Stents or metal endoprotheses are currently used to prevent restenosis after percutaneous transluminal angioplasty (PTA). Recently multi-component systems comprising implant applications, e. g., stents, protective and/or a drug containing layers, have found wide-spread application. Permanent and biocompatible stent coatings based on polyp-xylylene) (PPX) films were investigated for their potential to form drug containing reservoirs. The model drug dexamethasone was loaded into films of PPX by solvent treatment. Loading efficiency and in vitro drug release profiles were studied under physiological conditions. Linear release of dexamethasone was observed when PPX/dexamethasone films were coated by an additional PPX film as cover layer.
Weitere Angaben
Publikationsform: | Artikel in einer Zeitschrift |
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Begutachteter Beitrag: | Ja |
Keywords: | dexamethasone; drug release; parylene; PPX; stent |
Institutionen der Universität: | Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie > Lehrstuhl Makromolekulare Chemie II > Lehrstuhl Makromolekulare Chemie II - Univ.-Prof. Dr. Andreas Greiner Fakultäten Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie > Lehrstuhl Makromolekulare Chemie II |
Titel an der UBT entstanden: | Nein |
Themengebiete aus DDC: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
Eingestellt am: | 01 Apr 2015 09:54 |
Letzte Änderung: | 24 Feb 2022 14:29 |
URI: | https://eref.uni-bayreuth.de/id/eprint/9560 |