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Electrospinning approaches toward scaffold engineering - A brief overview

Title data

Boudriot, Ulrich ; Dersch, Roland ; Greiner, Andreas ; Wendorff, Joachim H.:
Electrospinning approaches toward scaffold engineering - A brief overview.
In: Artificial Organs. Vol. 30 (October 2006) Issue 10 . - pp. 785-792.
ISSN 1525-1594
DOI: https://doi.org/10.1111/j.1525-1594.2006.00301.x

Official URL: Volltext

Abstract in another language

Tissue engineering involves the in vitro seeding of cells onto scaffolds which assume the role of supporting cell adhesion, migration, proliferation, and differentiation, and which define the three-dimensional shape of the tissue to be engineered. Among the various types of scaffold architectures available, scaffolds based on nanofibers mimicking to a certain extent the structure of the extracellular matrix offer great advantages. Electrospinning is the technique of choice for the preparation of such scaffolds. Investigations have revealed that the nanofibrous structure promotes cell adhesion, proliferation, and differentiation. Parameters relevant for these processes such as fiber diameters, surface topology, porosity, mechanical properties, and the fibrous architecture of the scaffold can be controlled by electrospinning in a broad range.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: tissue engineering; nanofibrous scaffolds; electrospinning; coelectrospinning; biodegradable polymers; scaffold architecture
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Macromolecular Chemistry II > Chair Macromolecular Chemistry II - Univ.-Prof. Dr. Andreas Greiner
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Macromolecular Chemistry II
Result of work at the UBT: No
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 13 Apr 2015 06:35
Last Modified: 13 Apr 2015 06:35
URI: https://eref.uni-bayreuth.de/id/eprint/9684