Titelangaben
Boudriot, Ulrich ; Götz, Bernhard ; Dersch, Roland ; Greiner, Andreas ; Wendorff, Joachim H.:
Role of electrospun nanofibers in stem cell technologies and tissue engineering.
In: Macromolecular Symposia.
Bd. 225
(2005)
Heft 1
.
- S. 9-16.
ISSN 1521-3900
DOI: https://doi.org/10.1002/masy.200550702
Abstract
Tissue engineering is a promising toot to manage structural and functional defects in bone and cartilage. To provide optimal conditions for three-dimensional cell growth the use of a scaffold is necessary. The aim of the study was to prove osteogenic differentiation of human mesenchymal stem cells (hMSC) onto a three-dimensional, nanostructured scaffold of electrospun poly (1-lactide)-nanofibers. HMSC were seeded onto this matrix and differentiated for 21 days. Cells clearly preferred a guided growth along the nanofibers and revealed no signs of cell-death. Osteogenic differentiation of hMSC onto the matrix has been demonstrated. Due to the fine structure, electrospun nanofibers promises to be an ideal scaffold for tissue engineering. They can be enriched with additives and are equally biocompatible and biodegradable.
Weitere Angaben
Publikationsform: | Artikel in einer Zeitschrift |
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Begutachteter Beitrag: | Nein |
Keywords: | biomaterials; mesenchymal stem cells; nanofibers; nanotechnology; tissue engineering |
Institutionen der Universität: | Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie > Lehrstuhl Makromolekulare Chemie II > Lehrstuhl Makromolekulare Chemie II - Univ.-Prof. Dr. Andreas Greiner Fakultäten Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie > Lehrstuhl Makromolekulare Chemie II |
Titel an der UBT entstanden: | Ja |
Themengebiete aus DDC: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
Eingestellt am: | 13 Apr 2015 13:13 |
Letzte Änderung: | 21 Dec 2023 10:27 |
URI: | https://eref.uni-bayreuth.de/id/eprint/9701 |