at Google ScholarTitle data
Kupper, Maria ; Gupta, Shishir K. ; Feldhaar, Heike ; Gross, Roy:
Versatile roles of the chaperonin GroEL in microorganism : insect interactions.
In: FEMS Microbiology Letters.
Vol. 353
(2014)
.
- pp. 1-10.
ISSN 1574-6968
DOI: https://doi.org/10.1111/1574-6968.12390
Abstract in another language
The chaperonin 60 (Cpn60) is present in all three kingdoms of life and is one of the most conserved proteins in living organisms. The Escherichia coli Cpn60 (GroEL) is the best studied representative of the huge Cpn60 family. It is an essential protein because in conjunction with the chaperonin 10 (Cpn10 or GroES) it forms a protein-folding machine required for correct folding of many proteins and for recycling of misfolded proteins. As many other chaperones, GroEL and GroES are also known as heat-shock proteins (HSPs), since heat stress leads to a strong induction of their expression, a measure to counteract the increase in misfolded proteins as a result of a high nonphysiological temperature. A large amount of literature is available which is dedicated to the elucidation of how protein folding is assisted by this molecular chaperone. However, apart from this primary task, additional so-called moonlighting' functions of GroEL proteins unrelated to their folding activity have emerged in the past years. In fact, it becomes apparent that GroEL proteins have diverse functions in particular in mutualistic and pathogenic microorganism-host interactions. In this brief review, we describe some of these recent findings focusing on the importance of GroEL for microorganism-insect interactions.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Additional notes: | BAYCEER122486 |
| Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Animal Ecology I Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Professor Animal Population Ecology > Professor Animal Population Ecology - Univ.-Prof. Dr. Heike Feldhaar Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Professor Animal Population Ecology |
| Result of work at the UBT: | No |
| DDC Subjects: | 500 Science > 500 Natural sciences 500 Science > 570 Life sciences, biology 500 Science > 590 Animals (Zoology) |
| Date Deposited: | 24 Apr 2015 08:56 |
| Last Modified: | 05 Jun 2023 13:21 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/10799 |