Title data
Krebs, Herbert ; Schmid, Franz X. ; Jaenicke, Rainer:
Native-like folding intermediates of homologous ribonucleases.
In: Biochemistry.
Vol. 24
(1985)
Issue 15
.
- pp. 3846-3852.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00336a005
Related URLs
Abstract in another language
The mechanism of the slow refolding reactions of four different pancreatic ribonucleases from ox, sheep, red deer, and roe deer has been investigated. Refolding kinetics of these proteins were very similar. In particular, a native-like intermediate, IN, was shown to be populated on the slow refolding pathway of all ribonucleases. We conclude that, similar to the stability of the folded proteins, the pathway of slow refolding has been conserved despite the differences in amino acid sequence and the varying number of proline residues.
Further data
Item Type: | Article in a journal |
---|---|
Refereed: | Yes |
Additional notes: | PubMed-ID: 4052370 |
Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors > Professor Biochemistry - Univ.-Prof. Dr. Franz Xaver Schmid Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Professorship Biochemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors |
Result of work at the UBT: | No |
DDC Subjects: | 500 Science > 540 Chemistry |
Date Deposited: | 30 Apr 2015 10:59 |
Last Modified: | 20 Apr 2022 12:34 |
URI: | https://eref.uni-bayreuth.de/id/eprint/11225 |