at Google ScholarTitle data
Davidov, Geula ; Müller, Frank-Dietrich ; Baumgartner, Jens ; Bitton, Ronit ; Faivre, Damien ; Schüler, Dirk ; Zarivach, Raz:
Crystal structure of the magnetobacterial protein MtxA C-terminal domain reveals a new sequence-structure relationship.
In: Frontiers in Molecular Biosciences.
Vol. 2
(2015)
.
- pp. 1-13.
ISSN 2296-889X
DOI: https://doi.org/10.3389/fmolb.2015.00025
Abstract in another language
Magnetotactic bacteria (MTB) are a diverse group of aquatic bacteria that have the magnetotaxis ability to align themselves along the geomagnetic field lines and to navigate to a microoxic zone at the bottom of chemically stratified natural water. This special navigation is the result of a unique linear assembly of a specialized organelle, the magnetosome, which contains a biomineralized magnetic nanocrystal enveloped by a cytoplasmic membrane. The Magnetospirillum gryphiswaldense MtxA protein (MGR_0208) was suggested to play a role in bacterial magnetotaxis due to its gene location in an operon together with putative signal transduction genes. Since no homology is found for MtxA, and to better understand the role and function of MtxA in MTBés magnetotaxis, we initiated structural and functional studies of MtxA via X-ray crystallography and deletion mutagenesis. Here, we present the crystal structure of the MtxA C-terminal domain and provide new insights into its sequence-structure relationship.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Keywords: | MtxA; magnetotactic bacteria; magnetosome genomic island; magnetotaxis; magnetosome; tetratricopeptide repeats; immunoglobulin-like domain |
| Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Microbiology > Chair Microbiology - Univ.-Prof. Dr. Dirk Schüler Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Microbiology |
| Result of work at the UBT: | Yes |
| DDC Subjects: | 500 Science 500 Science > 500 Natural sciences 500 Science > 570 Life sciences, biology |
| Date Deposited: | 01 Dec 2016 12:46 |
| Last Modified: | 07 Mar 2023 14:23 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/18131 |