at Google ScholarTitle data
Zakharchenko, Svetlana ; Sperling, Evgeni ; Ionov, Leonid:
Fully Biodegradable Self-Rolled Polymer Tubes : a Candidate for Tissue Engineering Scaffolds.
In: Biomacromolecules.
Vol. 12
(2011)
Issue 6
.
- pp. 2211-2215.
ISSN 1526-4602
DOI: https://doi.org/10.1021/bm2002945
Abstract in another language
We report an approach for the fabrication of fully biodegradable self-rolled tubes based on patterned polysuccinimide/polycaprolactone bilayers. These polymers are biocompatible, biodegradable, produced industrially, and are already approved for biomedical purposes. Both polycaprolactone and polysuccinimide are hydrophobic and intrinsically water-insoluble. Polysuccinimide, however, hydrolyzes in physiological buffer environment yielding water-swellable polyaspartic acid that causes the rolling of the polymer bilayer and formation of tubes. We demonstrate the possibility to encapsulate yeast cells using self-rolled tubes.We report an approach for the fabrication of fully biodegradable self-rolled tubes based on patterned polysuccinimide/polycaprolactone bilayers. These polymers are biocompatible, biodegradable, produced industrially, and are already approved for biomedical purposes. Both polycaprolactone and polysuccinimide are hydrophobic and intrinsically water-insoluble. Polysuccinimide, however, hydrolyzes in physiological buffer environment yielding water-swellable polyaspartic acid that causes the rolling of the polymer bilayer and formation of tubes. We demonstrate the possibility to encapsulate yeast cells using self-rolled tubes.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Engineering Science > Professor Biofabrication > Professor Biofabrication - Univ.-Prof. Dr. Leonid Ionov Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Professor Biofabrication |
| Result of work at the UBT: | Yes |
| DDC Subjects: | 500 Science > 540 Chemistry |
| Date Deposited: | 21 Jun 2017 11:21 |
| Last Modified: | 09 Mar 2022 14:26 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/37710 |