Title data
Ionov, Leonid ; Stamm, Manfred ; Diez, Stefan:
Size Sorting of Protein Assemblies Using Polymeric Gradient Surfaces.
In: Nano Letters.
Vol. 5
(2005)
Issue 10
.
- pp. 1910-1914.
ISSN 1530-6992
DOI: https://doi.org/10.1021/nl051235h
Abstract in another language
We report on a novel approach for the size-dependent fractionation of protein assemblies on polymeric surfaces. Using a simple temperature gradient method to generate one-dimensional gradients of grafted poly(ethylene glycol), we fabricated silicon-oxide chips with a gradually changing surface density of kinesin motor molecules. We demonstrate that such a bioactive surface can be used to sort gliding microtubules according to their length. To our knowledge, this is the first example of the self-organized sorting of protein assemblies on surfaces.We report on a novel approach for the size-dependent fractionation of protein assemblies on polymeric surfaces. Using a simple temperature gradient method to generate one-dimensional gradients of grafted poly(ethylene glycol), we fabricated silicon-oxide chips with a gradually changing surface density of kinesin motor molecules. We demonstrate that such a bioactive surface can be used to sort gliding microtubules according to their length. To our knowledge, this is the first example of the self-organized sorting of protein assemblies on surfaces.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Engineering Science > Professor Biofabrication > Professor Biofabrication - Univ.-Prof. Dr. Leonid Ionov Faculties Faculties > Faculty of Engineering Science Faculties > Faculty of Engineering Science > Professor Biofabrication |
| Result of work at the UBT: | Yes |
| DDC Subjects: | 500 Science > 540 Chemistry |
| Date Deposited: | 22 Jun 2017 15:05 |
| Last Modified: | 09 Mar 2022 14:07 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/37760 |

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