Monodisperse collagen-gelatin beads as potential platforms for 3D cell culturing

Title data

Ma, Shaohua ; Natoli, Manuela ; Liu, Xin ; Neubauer, Martin Peter ; Watt, Fiona M. ; Fery, Andreas ; Huck, Wilhelm T. S.:
Monodisperse collagen-gelatin beads as potential platforms for 3D cell culturing.
In: Journal of Materials Chemistry B. Vol. 1 (2013) Issue 38 . - pp. 5128-5136.
ISSN 2050-7518
DOI: https://doi.org/10.1039/C3TB20851F

Official URL:

Abstract in another language

A droplet-based microfluidics technique is used to produce monodisperse, 80 mm collagen--gelatin beads with tunable mechanical properties in the range of 1--10 kPa after photo-crosslinking. The gel beads are porous, mechanically robust and stable in buffer, but can be degraded enzymatically. Encapsulated fibroblast cells maintain 70 viability after one-week encapsulation and preliminary results show that the degree of spreading of cells in gels is correlated with the stiffness of the material.

Further data

Item Type:	Article in a journal
Refereed:	Yes
Institutions of the University:	Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors > Chair Physical Chemistry II - Univ.-Prof. Dr. Andreas Fery Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Physical Chemistry II Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors
Result of work at the UBT:	Yes
DDC Subjects:	500 Science > 500 Natural sciences 500 Science > 530 Physics 500 Science > 540 Chemistry
Date Deposited:	05 Dec 2014 07:44
Last Modified:	01 Feb 2022 13:19
URI:	https://eref.uni-bayreuth.de/id/eprint/3940