at Google ScholarTitle data
Schörner, Mario ; Beyer, Sebastian R. ; Southall, June ; Cogdell, Richard J. ; Köhler, Jürgen:
Conformational Memory of a Protein Revealed by Single-Molecule Spectroscopy.
In: The Journal of Physical Chemistry B.
Vol. 119
(2015)
Issue 44
.
- pp. 13964-13970.
ISSN 1520-5207
DOI: https://doi.org/10.1021/acs.jpcb.5b07494
Abstract in another language
Proteins are supramolecular machines that carry out a wide range of different functions, many of which require flexibility. Up until now spontaneous conformational fluctuations of proteins have always been assumed to reflect a stochastic random process. However, if changing between different conformational states was random, then it would be difficult to understand how conformational control of protein function could have evolved. Here we demonstrate that a single protein can show conformational memory. This is exactly the process that can facilitate the evolution of control of switching between two conformational states that can then be used to regulate protein function.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Chair Experimental Physics IX - Spectroscopy of Soft Matter > Chair Experimental Physics IX - Spectroscopy of Soft Matter - Univ.-Prof. Dr. Jürgen Köhler Faculties Faculties > Faculty of Mathematics, Physics und Computer Science Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Chair Experimental Physics IX - Spectroscopy of Soft Matter |
| Result of work at the UBT: | Yes |
| DDC Subjects: | 500 Science > 530 Physics |
| Date Deposited: | 10 Apr 2018 11:41 |
| Last Modified: | 11 Jan 2023 11:10 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/43399 |