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Quantitative Comparison of the Antimicrobial Efficiency of Leaching versus Nonleaching Polymer Materials

Title data

Bruenke, Joerg ; Roschke, Ingolf ; Agarwal, Seema ; Riemann, Thomas ; Greiner, Andreas:
Quantitative Comparison of the Antimicrobial Efficiency of Leaching versus Nonleaching Polymer Materials.
In: Macromolecular Bioscience. Vol. 16 (2016) Issue 5 . - pp. 647-654.
ISSN 1616-5195
DOI: https://doi.org/10.1002/mabi.201500266

Abstract in another language

New antimicrobial materials will be more and more in the focus for hygienic and clinical disease control. Antimicrobial materials have to be distinguished in leaching and nonleaching materials. For many applications of antimicrobial materials on implants the use of nonleaching materials is essential. Therefore, the antimicrobial efficiency of leaching and nonleaching polymers has been investigated quantitatively in vitro in direct comparison on a highly relevant implant of central venous catheters (CVCs) using a well‐established called Certika test. This test is especially designed to test antimicrobial properties of leachable and nonleachable materials. This contribution demonstrates that newly developed nonleaching antimicrobial CVCs are equivalent to conventional leaching CVC systems in their antimicrobial performance against gram‐positive and gram‐negative bacteria, as well as Candida species. The use of new nonleaching antimicrobial polymers as shown here for CVCs represents a different mode of action with the aim to prevent infections also with antibiotic‐resistant strains and reduced side effects.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Macromolecular Chemistry II
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Macromolecular Chemistry II > Chair Macromolecular Chemistry II - Univ.-Prof. Dr. Andreas Greiner
Faculties
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 14 Aug 2018 10:15
Last Modified: 14 Aug 2018 10:15
URI: https://eref.uni-bayreuth.de/id/eprint/45433