at Google ScholarTitle data
Rosin-Arbesfeld, Rina ; Willbold, Dieter ; Yaniv, Abraham ; Gazit, Arnona:
The Tat protein of equine infectious anemia virus (EIAV) activates cellular gene expression by read-through transcription.
In: Gene.
Vol. 219
(1998)
Issue 1-2
.
- pp. 25-35.
ISSN 1879-0038
DOI: https://doi.org/10.1016/S0378-1119(98)00389-8
Abstract in another language
The Tat protein of equine infectious anemia virus, EIAV, was shown to augment viral gene expression, presumably through interaction with the Tat responsive element, TAR. Recently, cell-free polyadenylation assays suggested that perturbation of the EIAV TAR secondary structure diminished polyadenylation efficiency. The present study indicates that the EIAV TAR regulates the efficiency of the 3′-end processing of viral RNA also in transfected cells. Moreover, our data suggest that the provision of the EIAV Tat protein in trans potentiates read-through transcription through the 3′ viral long terminal repeat (3′ LTR), thus suggesting activation of downstream-located cellular genes.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors > Chair Biopolymers - Univ.-Prof. Dr. Paul Rösch Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry with an Emphasis on Biophysical Chemistry |
| Result of work at the UBT: | Yes |
| DDC Subjects: | 500 Science > 540 Chemistry 500 Science > 570 Life sciences, biology |
| Date Deposited: | 23 Jan 2019 10:11 |
| Last Modified: | 14 Nov 2022 11:38 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/46998 |