Enlarging the toolbox for allergen epitope definition with an allergen-type model protein

Title data

Berkner, Hanna ; Seutter von Loetzen, Christian ; Hartl, Maximilian J. ; Randow, Stefanie ; Gubesch, Michaela ; Vogel, Lothar ; Husslik, Felix ; Reuter, Andreas ; Lidholm, Jonas ; Ballmer-Weber, Barbara ; Vieths, Stefan ; Rösch, Paul ; Schiller, Dirk:
Enlarging the toolbox for allergen epitope definition with an allergen-type model protein.
In: PLoS One. Vol. 9 (2014) Issue 10 . - e111691.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0111691

Official URL:

Abstract in another language

BACKGROUND: Birch pollen-allergic subjects produce polyclonal cross-reactive IgE antibodies that mediate pollen-associated food allergies. The major allergen Bet v 1 and its homologs in plant foods bind IgE in their native protein conformation. Information on location, number and clinical relevance of IgE epitopes is limited. We addressed the use of an allergen-related protein model to identify amino acids critical for IgE binding of PR-10 allergens.

Further data

Item Type:	Article in a journal
Refereed:	Yes
Institutions of the University:	Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry with an Emphasis on Biophysical Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors > Chair Biopolymers - Univ.-Prof. Dr. Paul Rösch Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors
Result of work at the UBT:	Yes
DDC Subjects:	500 Science 500 Science > 500 Natural sciences 500 Science > 540 Chemistry 500 Science > 570 Life sciences, biology
Date Deposited:	19 Dec 2014 09:30
Last Modified:	22 Nov 2023 10:26
URI:	https://eref.uni-bayreuth.de/id/eprint/5063