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Flexible and Modular Syntheses of Enantiopure 5-cis-Substituted Prolinamines from l-Pyroglutamic Acid

Title data

Prause, Felix ; Kaldun, Johannes ; Arensmeyer, Benjamin ; Wennemann, Benedikt ; Fröhlich, Benjamin ; Scharnagel, Dagmar ; Breuning, Matthias:
Flexible and Modular Syntheses of Enantiopure 5-cis-Substituted Prolinamines from l-Pyroglutamic Acid.
In: Synthesis. Vol. 47 (2015) Issue 4 . - pp. 575-586.
ISSN 0039-7881
DOI: https://doi.org/10.1055/s-0034-1379457

Abstract in another language

A wide range (25 examples) of 5-cis-substituted prolinamines is prepared in five to ten steps starting from cheap l-pyroglutamic acid. Three routes, differing mainly in the order of introduction of the substituents at the 5-cis position, the pyrrolidine nitrogen atom, and the exocyclic amino function, are successfully developed.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: amines; ligands; stereoselective synthesis; pyrrolidines; prolinamines
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Professor Organic Chemistry > Professor Organic Chemistry - Univ.-Prof. Dr. Matthias Breuning
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Professor Organic Chemistry
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 11 Jan 2022 13:00
Last Modified: 11 Jan 2022 13:00
URI: https://eref.uni-bayreuth.de/id/eprint/68302