at Google ScholarTitle data
Mühlig, Anna ; Bocklitz, Thomas ; Labugger, Ines ; Dees, Stefan ; Henk, Sandra ; Richter, Elvira ; Andres, Sönke ; Merker, Matthias ; Stöckel, Stephan ; Weber, Karina ; Cialla-May, Dana ; Popp, Jürgen:
LOC-SERS : A Promising Closed System for the Identification of Mycobacteria.
In: Analytical Chemistry.
Vol. 88
(2016)
Issue 16
.
- pp. 7998-8004.
ISSN 1520-6882
DOI: https://doi.org/10.1021/acs.analchem.6b01152
Abstract in another language
A closed droplet based lab-on-a-chip (LOC) device has been developed for the differentiation of six species of mycobacteria, i.e., both Mycobacterium tuberculosis complex (MTC) and nontuberculous mycobacteria (NTM), using surface-enhanced Raman spectroscopy (SERS). The combination of a fast and simple bead-beating module for the disruption of the bacterial cell with the LOC-SERS device enables the application of an easy and reliable system for bacteria discrimination. Without extraction or further treatment of the sample, the obtained SERS spectra are dominated by the cell-wall component mycolic acid. For the differentiation, a robust data set was recorded using a droplet based LOC-SERS device. Thus, more than 2100 individual SERS spectra of the bacteria suspension were obtained in 1 h. The differentiation of bacteria using LOC-SERS provides helpful information for physicians to define the conditions for the treatment of individual patients.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Computer Science > Lehrstuhl Künstliche Intelligenz in der Mikroskopie und Spektroskopie > Lehrstuhl Künstliche Intelligenz in der Mikroskopie und Spektroskopie - Univ.-Prof. Dr. Thomas Wilhelm Bocklitz |
| Result of work at the UBT: | No |
| DDC Subjects: | 500 Science > 530 Physics |
| Date Deposited: | 15 May 2023 13:52 |
| Last Modified: | 15 May 2023 13:52 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/76345 |