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Designte Spinnenseidenmaterialien für zellspezifische Interaktionen

Title data

Trossmann, Vanessa T. ; Scheibel, Thomas:
Designte Spinnenseidenmaterialien für zellspezifische Interaktionen.
In: BIOspektrum. Vol. 29 (2023) . - pp. 689-691.
ISSN 1868-6249
DOI: https://doi.org/10.1007/s12268-023-2026-4

Official URL: Volltext

Abstract in another language

Spider silk films are promising for regenerative medicine and tissue engineering due to their biocompatibility. However, without modifications spider silk films often interact little with cells. Thus, we developed two modification strategies to enhance and guide specific cell interaction: 1) We introduced topographical surface patterns as cellular anchoring points. 2) We fused short cell adhesive peptide sequences to spider silk providing chemical interaction sites for cell receptors.

Further data

Item Type: Article in a journal
Refereed: No
Institutions of the University: Faculties > Faculty of Engineering Science > Chair Biomaterials > Chair Biomaterials - Univ.-Prof. Dr. Thomas Scheibel
Faculties
Faculties > Faculty of Engineering Science
Faculties > Faculty of Engineering Science > Chair Biomaterials
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 570 Life sciences, biology
Date Deposited: 10 Nov 2023 07:07
Last Modified: 21 Dec 2023 07:15
URI: https://eref.uni-bayreuth.de/id/eprint/87496