at Google ScholarTitle data
Englert, Christoph ; Brendel, Johannes C. ; Majdanski, Tobias C. ; Yildirim, Turgay ; Schubert, Stephanie ; Gottschaldt, Michael ; Windhab, Norbert ; Schubert, Ulrich S.:
Pharmapolymers in the 21st century : Synthetic polymers in drug delivery applications.
In: Progress in Polymer Science.
Vol. 87
(2018)
.
- pp. 107-164.
ISSN 0079-6700
DOI: https://doi.org/10.1016/j.progpolymsci.2018.07.005
Abstract in another language
The administration of drugs, as a main challenge of pharmaceutical and medicinal applications, has certainly benefited from the application of synthetic polymers. However, despite an enormous effort to develop new materials for drug delivery applications, only few of them have entered the market due to the hurdles of regulation, production, cost efficiency and both industrial’s and patients’ acceptance. In this review, we summarize all these classes of synthetic polymers, which are on the market as well as the latest developments in clinical trials, and describe their application in polymer-drug conjugates, as excipients, in nano-/microscopic and macroscopic drug carriers, as polymeric coatings, or as polymeric drugs. Our intention is to create a link between the underlying chemical structures, the properties of the polymers, and their area of application, where they are often just known by their trade names or abbreviations. In addition selected types of synthetic polymers are highlighted that feature interesting properties and have the potential to make it to the market in future.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Keywords: | Pharmapolymers; Drug delivery; Market; Clinical trials; Structure-activity relationships |
| Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Macromolecular Chemistry I Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Macromolecular Chemistry I > Chair Macromolecular Chemistry I - Univ.-Prof. Dr. Johannes C. Brendel |
| Result of work at the UBT: | No |
| DDC Subjects: | 500 Science > 540 Chemistry |
| Date Deposited: | 21 Feb 2024 07:21 |
| Last Modified: | 02 May 2024 07:39 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/88575 |