bei Google ScholarTitelangaben
Rho, Julia Y. ; Cox, Henry ; Mansfield, Edward D. H. ; Ellacott, Sean H. ; Peltier, Raoul ; Brendel, Johannes C. ; Hartlieb, Matthias ; Waigh, Thomas A. ; Perrier, Sébastien:
Dual self-assembly of supramolecular peptide nanotubes to provide stabilisation in water.
In: Nature Communications.
Bd. 10
(2019)
.
- 4708.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-019-12586-8
Abstract
Self-assembling peptides have the ability to spontaneously aggregate into large ordered structures. The reversibility of the peptide hydrogen bonded supramolecular assembly make them tunable to a host of different applications, although it leaves them highly dynamic and prone to disassembly at the low concentration needed for biological applications. Here we demonstrate that a secondary hydrophobic interaction, near the peptide core, can stabilise the highly dynamic peptide bonds, without losing the vital solubility of the systems in aqueous conditions. This hierarchical self-assembly process can be used to stabilise a range of different β-sheet hydrogen bonded architectures.
Weitere Angaben
| Publikationsform: | Artikel in einer Zeitschrift |
|---|---|
| Begutachteter Beitrag: | Ja |
| Institutionen der Universität: | Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Chemie > Lehrstuhl Makromolekulare Chemie I |
| Titel an der UBT entstanden: | Nein |
| Themengebiete aus DDC: | 500 Naturwissenschaften und Mathematik > 540 Chemie |
| Eingestellt am: | 19 Feb 2024 14:46 |
| Letzte Änderung: | 19 Feb 2024 14:46 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/88611 |