Molecular Crowding : The History and Development of a Scientific Paradigm

Title data

Alfano, Caterina ; Fichou, Yann ; Huber, Klaus ; Weiss, Matthias ; Spruijt, Evan ; Ebbinghaus, Simon ; De Luca, Giuseppe ; Morando, Maria Agnese ; Vetri, Valeria ; Temussi, Piero Andrea ; Pastore, Annalisa:
Molecular Crowding : The History and Development of a Scientific Paradigm.
In: Chemical Reviews. Vol. 124 (March 2024) Issue 6 . - pp. 3186-3219.
ISSN 0009-2665
DOI: https://doi.org/10.1021/acs.chemrev.3c00615

Official URL:

Abstract in another language

It is now generally accepted that macromolecules do not act in isolation but “live” in a crowded environment, that is, an environment populated by numerous different molecules. The field of molecular crowding has its origins in the far 80s but became accepted only by the end of the 90s. In the present issue, we discuss various aspects that are influenced by crowding and need to consider its effects. This Review is meant as an introduction to the theme and an analysis of the evolution of the crowding concept through time from colloidal and polymer physics to a more biological perspective. We introduce themes that will be more thoroughly treated in other Reviews of the present issue. In our intentions, each Review may stand by itself, but the complete collection has the aspiration to provide different but complementary perspectives to propose a more holistic view of molecular crowding.

Further data

Item Type:	Article in a journal
Refereed:	Yes
Institutions of the University:	Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Chair Experimental Physics I - Physics of Living Matter > Chair Experimental Physics I - Physics of Living Matter - Univ.-Prof. Dr. Matthias Weiss Faculties Faculties > Faculty of Mathematics, Physics und Computer Science Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics Faculties > Faculty of Mathematics, Physics und Computer Science > Department of Physics > Chair Experimental Physics I - Physics of Living Matter
Result of work at the UBT:	Yes
DDC Subjects:	500 Science > 530 Physics 500 Science > 570 Life sciences, biology
Date Deposited:	07 May 2024 06:40
Last Modified:	13 May 2024 05:23
URI:	https://eref.uni-bayreuth.de/id/eprint/89489