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Borane-Catalyzed Carbazolation Reactions of Aryldiazoacetates

Title data

He, Feifei ; Koenigs, Rene M.:
Borane-Catalyzed Carbazolation Reactions of Aryldiazoacetates.
In: Organic Letters. Vol. 23 (2021) . - pp. 5831-5835.
ISSN 1523-7052
DOI: https://doi.org/10.1021/acs.orglett.1c01982

Abstract in another language

Herein, we report on the tris(pentafluorophenyl)borane-catalyzed reaction of carbazole heterocycles with aryldiazoacetates. We could demonstrate that selective N–H functionalization occurs in the case of an unprotected carbazole, other N-heterocycles, and secondary amines in good yields. In contract, the protected carbazole undergoes C–H functionalization at the C-3 position in a good yield. The application of both approaches was studied in 41 examples with up to a 97% yield.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry - Univ.-Prof. Dr. René M. Koenigs
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry
Result of work at the UBT: No
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 01 Apr 2025 11:26
Last Modified: 14 May 2025 07:54
URI: https://eref.uni-bayreuth.de/id/eprint/93112