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Tropylium-Catalyzed O–H Insertion Reactions of Diazoalkanes with Carboxylic Acids

Title data

Empel, Claire ; Nguyen, Thanh Vinh ; Koenigs, Rene M.:
Tropylium-Catalyzed O–H Insertion Reactions of Diazoalkanes with Carboxylic Acids.
In: Organic Letters. Vol. 23 (2021) . - pp. 548-553.
ISSN 1523-7052
DOI: https://doi.org/10.1021/acs.orglett.0c04069

Abstract in another language

Herein, we describe the application of a nonbenzenoid aromatic carbocation, namely tropylium, as an organic Lewis acid catalyst in O–H functionalization reactions of diazoalkanes with benzoic acids. The newly developed protocol is applicable to a wide range of diazoalkane and carboxylic acid substrates with excellent efficiency (43 examples, up to 99% yield).

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry - Univ.-Prof. Dr. René M. Koenigs
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry
Result of work at the UBT: No
DDC Subjects: 500 Science > 540 Chemistry
Date Deposited: 01 Apr 2025 11:49
Last Modified: 07 Oct 2025 10:59
URI: https://eref.uni-bayreuth.de/id/eprint/93118