at Google ScholarTitle data
Mykhailiuk, Pavel K. ; Koenigs, Rene M.:
Difluorodiazoethane (CF₂HCHN₂): A New Reagent for the Introduction of the Difluoromethyl Group.
In: Chemistry : a European Journal.
Vol. 25
(2019)
.
- pp. 6053-6063.
ISSN 1521-3765
DOI: https://doi.org/10.1002/chem.201804953
Abstract in another language
Difluorodiazoethane (CF2HCHN2) is a small reactive diazoalkane. Its synthesis has been pursued since the 1970s, although only in the past three years have considerable advances been made. Today, difluorodiazoethane is a versatile reagent applied in [3+2]-cycloadditions, esterification, and carbene transfer reactions. Difluorodiazoethane possesses markedly altered reactivity compared to the well-studied trifluorodiazoethane (CF3CHN2). In this article, we discuss the differences between the two reagents: CF2HCHN2 and CF3CHN2. We highlight applications of difluorodiazoethane in organic synthesis, discuss bench-stable analogues, and its unexplored areas.
Further data
| Item Type: | Article in a journal |
|---|---|
| Refereed: | Yes |
| Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry - Univ.-Prof. Dr. René M. Koenigs Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry II - Bioorganic Chemistry |
| Result of work at the UBT: | No |
| DDC Subjects: | 500 Science > 540 Chemistry |
| Date Deposited: | 02 Apr 2025 12:53 |
| Last Modified: | 14 May 2025 07:54 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/93178 |