Photo-Driven Difunctionalization of Unactivated Alkenes : Recent Advances in Radical-Mediated Strategies

Title data

Maiti, Rakesh ; Das, Shoubhik:
Photo-Driven Difunctionalization of Unactivated Alkenes : Recent Advances in Radical-Mediated Strategies.
In: Synthesis. (22 April 2026) .
ISSN 0039-7881
DOI: https://doi.org/10.1055/a-2800-8016

Official URL:

Abstract in another language

The difunctionalization of alkenes serves as a powerful strategy for the simultaneous incorporation of two distinct functional groups across a carbon–carbon double bond, thereby enabling a rapid increase in molecular complexity. This transformation has found widespread application in modern organic synthesis due to its efficiency and versatility. In recent years, the advent of green and sustainable activation platforms, particularly using photochemistry, has significantly advanced this field. This mild and environmentally benign methodology has inspired innovative strategies for transforming abundant alkene and alkane feedstocks to complex scaffolds through radical pathways. In this review, we summarize recent progress in photo-driven alkene difunctionalization processes. Particular emphasis is placed on the unactivated alkenes, reaction design, and the mechanistic features of these transformations.

Further data

Item Type:	Article in a journal
Refereed:	Yes
Keywords:	difunctionalization; unactivated alkene; sustainable methods; photo-driven; radical
Institutions of the University:	Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Organic Chemistry I - Photo- und Elektrokatalyse für Nachhaltigkeit > Chair Organic Chemistry I - Photo- und Elektrokatalyse für Nachhaltigkeit - Univ.-Prof. Dr. Shoubhik Das
Result of work at the UBT:	Yes
DDC Subjects:	500 Science > 540 Chemistry
Date Deposited:	12 May 2026 06:26
Last Modified:	12 May 2026 06:26
URI:	https://eref.uni-bayreuth.de/id/eprint/97028