Yta7, a chromatin segregase regulated by the cell cycle machinery

Titelangaben

Bansal, Priyanka ; Kurat, Christoph F.:
Yta7, a chromatin segregase regulated by the cell cycle machinery.
In: Molecular & Cellular Oncology. Bd. 9 (2022) Heft 1 . - 2039577.
ISSN 2372-3556
DOI: https://doi.org/10.1080/23723556.2022.2039577

Angaben zu Projekten

Abstract

We have recently revealed the existence of a cell cycle-regulated chromatin segregase, Yta7 (Yeast Tat-binding Analog 7), involved in chromosome replication. Phosphorylation of Yta7 by S-CDK (S-phase Cyclin-Dependent Kinase) regulates its function. These findings link the cell cycle to chromatin biology and suggest how chromatin-modifying enzymes become S phase-specific.