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Regulation of histone gene transcription in yeast

Titelangaben

Kurat, Christoph F. ; Recht, Judith ; Radovani, Ernest ; Durbic, Tanja ; Andrews, Brenda ; Fillingham, Jeffrey:
Regulation of histone gene transcription in yeast.
In: Cellular and Molecular Life Sciences. Bd. 71 (2014) . - S. 599-613.
ISSN 1420-9071
DOI: https://doi.org/10.1007/s00018-013-1443-9

Abstract

Histones are the primary protein component of chromatin, the mixture of DNA and proteins that packages the genetic material in eukaryotes. Large amounts of histones are required during the S phase of the cell cycle when genome replication occurs. However, ectopic expression of histones during other cell cycle phases is toxic; thus, histone expression is restricted to the S phase and is tightly regulated at multiple levels, including transcriptional, post-transcriptional, translational, and post-translational. In this review, we discuss mechanisms of regulation of histone gene expression with emphasis on the transcriptional regulation of the replication-dependent histone genes in the model yeast Saccharomyces cerevisiae.

Weitere Angaben

Publikationsform: Artikel in einer Zeitschrift
Begutachteter Beitrag: Ja
Institutionen der Universität: Fakultäten > Fakultät für Biologie, Chemie und Geowissenschaften > Fachgruppe Biologie
Titel an der UBT entstanden: Nein
Themengebiete aus DDC: 500 Naturwissenschaften und Mathematik > 500 Naturwissenschaften
Eingestellt am: 06 Aug 2026 07:54
Letzte Änderung: 06 Aug 2026 07:54
URI: https://eref.uni-bayreuth.de/id/eprint/99212