Title data
Chemoenzymatic Synthesis of Natural Products and Complex Small Molecules.
ed.: Hahn, Frank
Cambridge, UK
:
Royal Society of Chemistry
,
2026
. -
xv, 512 p.
- (Chemical Biology
; 25
)
ISBN 978-1-83767-251-6
DOI: https://doi.org/10.1039/9781837677436
Abstract in another language
The total synthesis of structurally complex natural products has challenged and inspired generations of chemists. However, despite their history as privileged bioactivity-rich scaffolds, the use of natural products in drug discovery has waned. Recent developments in biocatalysis have resulted in the application of enzymes for the construction of complex molecules. This dynamically developing field is increasingly becoming a competitive alternative for classical total synthesis. Giving readers an in-depth overview of the current state of the field, this book will be of wide interest to natural products and drug researchers with a chemical or biochemical background and biocatalysis experts in academia and industry. Chapters include emerging enzymes from biosynthetic pathways, enzymes for building block synthesis and late-stage derivatisation as well as the formation of specific structural elements, such as chiral amines and heterocycles. Other important aspects for the efficient chemoenzymatic synthesis of bioactive molecules include the development of multi-enzyme cascades, engineered enzymes and strategic considerations for the use of biocatalysts in the synthesis of natural products and synthetic drugs.
Further data
| Item Type: | Book / Monograph |
|---|---|
| Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Professor Organische Chemie IV - Biotechnologie und Chemie der Lebensmittel und Wirkstoffe > Professor Organische Chemie IV - Biotechnologie und Chemie der Lebensmittel und Wirkstoffe - Univ.-Prof. Dr. Frank Hahn |
| Result of work at the UBT: | Yes |
| DDC Subjects: | 500 Science > 540 Chemistry |
| Date Deposited: | 23 Sep 2026 09:18 |
| Last Modified: | 23 Sep 2026 09:18 |
| URI: | https://eref.uni-bayreuth.de/id/eprint/99472 |