Institutionen der Universität Bayreuth
Lehrstuhl Molekulare Sportphysiologie

Fragoulis, Athanassios ; Tohidnezhad, Mersedeh ; Kubo, Yusuke ; Wruck, Christoph Jan ; Craveiro, Rogerio Bastos ; Bock, Anna ; Wolf, Michael ; Pufe, Thomas ; Jahr, Holger ; Suhr, Frank:
The Contribution of the Nrf2/ARE System to Mechanotransduction in Musculoskeletal and Periodontal Tissues.
In: International Journal of Molecular Sciences. Bd. 24 (2023) Heft 9 . - 7722.
DOI: https://doi.org/10.3390/ijms24097722

Rojo‐García, Ana Victoria ; Vanmunster, Mathias ; Pacolet, Alexander ; Suhr, Frank:
Physical inactivity by tail suspension alters markers of metabolism, structure, and autophagy of the mouse heart.
In: Physiological Reports. Bd. 11 (2023) Heft 2 . - e15574.
DOI: https://doi.org/10.14814/phy2.15574

Thievessen, Ingo ; Suhr, Frank ; Vergarajauregui, Silvia ; Böttcher, Ralph T. ; Brixius, Klara ; Rosenberger, Georg ; Dewald, Oliver ; Fleischmann, Bernd K. ; Ghanem, Alexander ; Krüger, Marcus ; Engel, Felix B. ; Fabry, Ben ; Bloch, Wilhelm ; Fässler, Reinhard:
The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load.
In: Current Biology. Bd. 32 (2022) Heft 14 . - 3033-3047.e9.
DOI: https://doi.org/10.1016/j.cub.2022.05.047

Vanmunster, Mathias ; Rojo Garcia, Ana Victoria ; Pacolet, Alexander ; Dalle, Sebastiaan ; Koppo, Katrien ; Jonkers, Ilse ; Lories, Rik ; Suhr, Frank:
Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism.
In: Cellular and Molecular Life Sciences. Bd. 79 (2022) Heft 6 . - 321.
DOI: https://doi.org/10.1007/s00018-022-04346-7

Andresen, Bernhard ; de Marees, Markus ; Schiffer, Thorsten ; Bloch, Wilhelm ; Suhr, Frank:
Skeletal muscle fiber type‐specific expressions of mechanosensors integrin‐linked kinase, talin, and vinculin and their modulation by loading and environmental conditions in humans.
In: The FASEB Journal. Bd. 36 (2022) Heft 8 . - e22458.
DOI: https://doi.org/10.1096/fj.202101377RR

Suhr, Frank ; Knuth, Sarah ; Achtzehn, Silvia ; Mester, Joachim ; de Marees, Markus:
Acute Exhaustive Exercise under Normoxic and Normobaric Hypoxic Conditions Differentially Regulates Angiogenic Biomarkers in Humans.
In: Medicina. Bd. 57 (2021) Heft 7 . - 727.
DOI: https://doi.org/10.3390/medicina57070727

Reuten, Raphael ; Zendehroud, Sina ; Nicolau, Monica ; Fleischhauer, Lutz ; Laitala, Anu ; Kiderlen, Stefanie ; Nikodemus, Denise ; Wullkopf, Lena ; Nielsen, Sebastian Rune ; McNeilly, Sarah ; Prein, Carina ; Rafaeva, Maria ; Schoof, Erwin M. ; Furtwängler, Benjamin ; Porse, Bo T. ; Kim, Hyobin ; Won, Kyoung Jae ; Sudhop, Stefanie ; Zornhagen, Kamilla Westarp ; Suhr, Frank ; Maniati, Eleni ; Pearce, Oliver M. T. ; Koch, Manuel ; Oddershede, Lene Broeng ; Van Agtmael, Tom ; Madsen, Chris D. ; Mayorca-Guiliani, Alejandro E. ; Bloch, Wilhelm ; Netz, Roland R. ; Clausen-Schaumann, Hauke ; Erler, Janine T.:
Basement membrane stiffness determines metastases formation.
In: Nature Materials. Bd. 20 (2021) Heft 6 . - S. 892-903.
DOI: https://doi.org/10.1038/s41563-020-00894-0

Dalle, Sebastiaan ; Van Roie, Evelien ; Hiroux, Charlotte ; Vanmunster, Mathias ; Coudyzer, Walter ; Suhr, Frank ; Bogaerts, Stijn ; Van Thienen, Ruud ; Koppo, Katrien:
Omega-3 supplementation improves isometric strength but not muscle anabolic and catabolic signaling in response to resistance exercise in healthy older adults.
In: The Journals of Gerontology Series A: Biological Sciences & Medical Sciences. Bd. 76 (2021) Heft 3 . - S. 406-414.
DOI: https://doi.org/10.1093/gerona/glaa309

Gnad, Thorsten ; Navarro, Gemma ; Lahesmaa, Minna ; Reverte-Salisa, Laia ; Copperi, Francesca ; Cordomi, Arnau ; Naumann, Jennifer ; Hochhäuser, Aileen ; Haufs-Brusberg, Saskia ; Wenzel, Daniela ; Suhr, Frank ; Jespersen, Naja Zenius ; Scheele, Camilla ; Tsvilovskyy, Volodymyr ; Brinkmann, Christian ; Rittweger, Joern ; Dani, Christian ; Kranz, Mathias ; Deuther-Conrad, Winnie ; Eltzschig, Holger K. ; Niemi, Tarja ; Taittonen, Markku ; Brust, Peter ; Nuutila, Pirjo ; Pardo, Leonardo ; Fleischmann, Bernd K. ; Blüher, Matthias ; Franco, Rafael ; Bloch, Wilhelm ; Virtanen, Kirsi A. ; Pfeifer, Alexander:
Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity.
In: Cell Metabolism. Bd. 32 (2020) Heft 1 . - S. 56-70.
DOI: https://doi.org/10.1016/j.cmet.2020.06.006

Dalle, Sebastiaan ; Poffé, Chiel ; Hiroux, Charlotte ; Suhr, Frank ; Deldicque, Louise ; Koppo, Katrien:
Ibuprofen does not Impair Skeletal Muscle Regeneration Upon Cardiotoxin-Induced Injury.
In: Physiological Research. Bd. 69 (2020) Heft 5 . - S. 847-859.
DOI: https://doi.org/10.33549/physiolres.934482

Suhr, Frank ; Braun, Kristina ; Vanmunster, Mathias ; Bloch, Wilhelm:
Acute Skeletal Muscle Contractions Orchestrate Signaling Mechanisms to Trigger Nuclear NFATc1 Shuttling and Epigenetic Histone Modifications.
In: Cellular Physiology and Biochemistry. Bd. 52 (2019) Heft 3 . - S. 633-652.
DOI: https://doi.org/10.33594/000000045

Mathes, Sebastian ; Vanmunster, Mathias ; Bloch, Wilhelm ; Suhr, Frank:
Evidence for skeletal muscle fiber type-specific expressions of mechanosensors.
In: Cellular and Molecular Life Sciences. Bd. 76 (2019) Heft 15 . - S. 2987-3004.
DOI: https://doi.org/10.1007/s00018-019-03026-3

Suhr, Frank:
Extracellular matrix, proteases and physical exercise.
In: Deutsche Zeitschrift für Sportmedizin. Bd. 70 (2019) Heft 4 . - S. 97-104.
DOI: https://doi.org/10.5960/dzsm.2019.367

Sahito, Raja Ghazanfar Ali ; Sheng, Xiaowu ; Maass, Martina ; Mikhael, Nelly ; Hamad, Sarkawt ; Heras-Bautista, Carlos O. ; Derichsweiler, Daniel ; Spitkovsky, Dimitry ; Suhr, Frank ; Khalil, Markus ; Brockmeier, Konrad ; Halbach, Marcel ; Saric, Tomo ; Hescheler, Jürgen ; Krausgrill, Benjamin ; Pfannkuche, Kurt:
In vitro grown micro-tissues for cardiac cell replacement therapy in vivo.
In: Cellular Physiology and Biochemistry. Bd. 52 (2019) Heft 6 . - S. 1309-1324.
DOI: https://doi.org/10.33594/000000092

Pingel, Jessica ; Suhr, Frank:
Are mechanically sensitive regulators involved in the function and (patho)physiology of cerebral palsy-related contractures?
In: Journal of Muscle Research and Cell Motility. Bd. 38 (2017) Heft 3-4 . - S. 317-330.
DOI: https://doi.org/10.1007/s10974-017-9489-1

Ackermans, Thijs Maria Anne ; Epro, Gaspar ; McCrum, Christopher ; Oberländer, Kai Daniel ; Suhr, Frank ; Drost, Maarten Robert ; Meijer, Kenneth ; Karamanidis, Kiros:
Aging and the effects of a half marathon on Achilles tendon force–elongation relationship.
In: European Journal of Applied Physiology. Bd. 116 (2016) Heft 11-12 . - S. 2281-2292.
DOI: https://doi.org/10.1007/s00421-016-3482-z

Gehlert, Sebastian ; Klinz, Franz Josef ; Willkomm, Lena ; Schiffer, Thorsten ; Suhr, Frank ; Bloch, Wilhelm:
Intense Resistance Exercise Promotes the Acute and Transient Nuclear Translocation of Small Ubiquitin-Related Modifier (SUMO)-1 in Human Myofibres.
In: International Journal of Molecular Sciences. Bd. 17 (2016) Heft 5 . - 646.
DOI: https://doi.org/10.3390/ijms17050646

Greiwe, L. ; Vinck, M. ; Suhr, Frank:
The muscle contraction mode determines lymphangiogenesis differentially in rat skeletal and cardiac muscles by modifying local lymphatic extracellular matrix microenvironments.
In: Acta Physiologica. Bd. 217 (2016) Heft 1 . - S. 61-79.
DOI: https://doi.org/10.1111/apha.12633

Grau, Marijke ; Lauten, Alexander ; Hoeppener, Steffen ; Goebel, Bjoern ; Brenig, Julian ; Jung, Christian ; Bloch, Wilhelm ; Suhr, Frank:
Regulation of red blood cell deformability is independent of red blood cell-nitric oxide synthase under hypoxia.
In: Clinical Hemorheology and Microcirculation. Bd. 63 (2016) Heft 3 . - S. 199-215.
DOI: https://doi.org/10.3233/CH-162044

Gehlert, Sebastian ; Bloch, Wilhelm ; Suhr, Frank:
Ca²⁺-dependent regulations and signaling in skeletal muscle : from electro-mechanical Coupling to Adaptation.
In: International Journal of Molecular Sciences. Bd. 16 (2015) Heft 1 . - S. 1066-1095.
DOI: https://doi.org/10.3390/ijms16011066

Grau, Marijke ; Friederichs, Petra ; Krehan, Sebastian ; Koliamitra, Christina ; Suhr, Frank ; Bloch, Wilhelm:
Decrease in red blood cell deformability is associated with a reduction in RBC-NOS activation during storage.
In: Clinical Hemorheology and Microcirculation. Bd. 60 (2015) Heft 2 . - S. 215-229.
DOI: https://doi.org/10.3233/CH-141850

Suhr, Frank:
Detection of fusion events in mammalian skeletal muscle.
In: Pfannkuche, Kurt (Hrsg.): Cell Fusion : Overviews and Methods. 2. Auflage. - New York : Humana Press, 2015 . - S. 115-129 . - (Methods in Molecular Biology ; 1313 )
DOI: https://doi.org/10.1007/978-1-4939-2703-6_8

Gehlert, Sebastian ; Suhr, Frank ; Gutsche, Katrin ; Willkomm, Lena ; Kern, Julia ; Jacko, Daniel ; Knicker, Axel ; Schiffer, Thorsten ; Wackerhage, Henning ; Bloch, Wilhelm:
High force development augments skeletal muscle signalling in resistance exercise modes equalized for time under tension.
In: Pflügers Archiv : European Journal of Physiology. Bd. 467 (2015) Heft 6 . - S. 1343-1356.
DOI: https://doi.org/10.1007/s00424-014-1579-y

Grau, Marijke ; Mozar, Anaïs ; Charlot, Keyne ; Lamarre, Yann ; Weyel, Linda ; Suhr, Frank ; Collins, Bianca ; Jumet, Stéphane ; Hardy-Dessources, Marie-Dominique ; Romana, Marc ; Lemonne, Nathalie ; Etienne-Julan, Maryse ; Antoine-Jonville, Sophie ; Bloch, Wilhelm ; Connes, Philippe:
High red blood cell nitric oxide synthase activation is not associated with improved vascular function and red blood cell deformability in sickle cell anaemia.
In: British Journal of Haematology. Bd. 168 (2015) Heft 5 . - S. 728-736.
DOI: https://doi.org/10.1111/bjh.13185

Frese, Sebastian ; Ruebner, Matthias ; Suhr, Frank ; Konou, Thierry M. ; Tappe, Kim A. ; Toigo, Marco ; Jung, Hans H. ; Henke, Christine ; Steigleder, Ruth ; Strissel, Pamela L. ; Huebner, Hanna ; Beckmann, Matthias W. ; van der Keylen, Piet ; Schoser, Benedikt ; Schiffer, Thorsten ; Frese, Laura ; Bloch, Wilhelm ; Strick, Reiner:
Long-Term Endurance Exercise in Humans Stimulates Cell Fusion of Myoblasts along with Fusogenic Endogenous Retroviral Genes In Vivo.
In: PLoS One. Bd. 10 (2015) Heft 7 . - e0132099.
DOI: https://doi.org/10.1371/journal.pone.0132099

Mozar, Anaïs ; Grau, Marijke ; Lamarre, Yann ; Weyel, Linda ; Suhr, Frank ; Collins, Bianca ; Hardy-Dessources, Marie-Dominique ; Romana, Marc ; Lemonne, Nathalie ; Etienne-Julan, Maryse ; Bloch, Wilhelm ; Connes, Philippe:
Red blood cell nitric oxide synthase activation is increased in patients with sickle cell hemoglobin C disease.
In: American Journal of Hematology. Bd. 90 (2015) Heft 2 . - E30-E32.
DOI: https://doi.org/10.1002/ajh.23894

Müller, Anna E. ; Kreiner, Matthias ; Kötter, Sebastian ; Lassak, Philipp ; Bloch, Wilhelm ; Suhr, Frank ; Krüger, Martina:
Acute exercise modifies titin phosphorylation and increases cardiac myofilament stiffness.
In: Frontiers in Physiology. Bd. 5 (2014) . - 449.
DOI: https://doi.org/10.3389/fphys.2014.00449

Bölck, Birgit ; Ibrahim, Marwa ; Steinritz, Dirk ; Morguet, Christian ; Dühr, Sandra ; Suhr, Frank ; Lu-Hesselmann, Juxian ; Bloch, Wilhelm:
Detection of key enzymes, free radical reaction products and activated signaling molecules as biomarkers of cell damage induced by benzo[a]pyrene in human keratinocytes.
In: Toxicology in Vitro. Bd. 28 (2014) Heft 5 . - S. 875-884.
DOI: https://doi.org/10.1016/j.tiv.2014.03.010

Attia, Wael A. ; Abd El Aziz, Osama M. ; Spitkovsky, Dimitry ; Gaspar, John A. ; Dröge, Peter ; Suhr, Frank ; Sabour, Davood ; Winkler, Johannes ; Meganathan, Kesavan ; Jagtap, Smita ; Khalil, Markus ; Hescheler, Jürgen ; Brockmeier, Konrad ; Sachinidis, Agapios ; Pfannkuche, Kurt:
Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies.
In: Stem Cell Reviews and Reports. Bd. 10 (2014) Heft 1 . - S. 1-15.
DOI: https://doi.org/10.1007/s12015-013-9472-1

Lauten, Alexander ; Gerhard-Garcia, Alexandra ; Suhr, Frank ; Fischer, Juergen H. ; Figulla, Hans R. ; Bloch, Wilhelm:
Impact of ischemia-reperfusion on extracellular matrix processing and structure of the basement membrane of the heart.
In: PLoS One. Bd. 9 (2014) Heft 3 . - e92833.
DOI: https://doi.org/10.1371/journal.pone.0092833

Willkomm, Lena ; Schubert, Sarah ; Jung, Raphael ; Elsen, Manuela ; Borde, Julika ; Gehlert, Sebastian ; Suhr, Frank ; Bloch, Wilhelm:
Lactate regulates myogenesis in C2C12 myoblasts in vitro.
In: Stem Cell Research. Bd. 12 (2014) Heft 3 . - S. 742-753.
DOI: https://doi.org/10.1016/j.scr.2014.03.004

Suhr, Frank ; Delhasse, Yvonne ; Bungartz, Gerd ; Schmidt, Annette ; Pfannkuche, Kurt ; Bloch, Wilhelm:
Cell biological effects of mechanical stimulations generated by focused extracorporeal shock wave applications on cultured human bone marrow stromal cells.
In: Stem Cell Research. Bd. 11 (2013) Heft 2 . - S. 951-964.
DOI: https://doi.org/10.1016/j.scr.2013.05.010

Grau, Marijke ; Pauly, Sebastian ; Ali, Jamal ; Walpurgis, Katja ; Thevis, Mario ; Bloch, Wilhelm ; Suhr, Frank:
RBC-NOS-dependent S-nitrosylation of cytoskeletal proteins improves RBC deformability.
In: PLoS One. Bd. 8 (2013) Heft 2 . - e56759.
DOI: https://doi.org/10.1371/journal.pone.0056759

Suhr, Frank ; Gehlert, Sebastian ; Grau, Marijke ; Bloch, Wilhelm:
Skeletal Muscle Function during Exercise : Fine-Tuning of Diverse Subsystems by Nitric Oxide.
In: International Journal of Molecular Sciences. Bd. 14 (2013) Heft 4 . - S. 7109-7139.
DOI: https://doi.org/10.3390/ijms14047109

Beijer, Åsa ; Rosenberger, André ; Bölck, Birgit ; Suhr, Frank ; Rittweger, Jörn ; Bloch, Wilhelm:
Whole-body vibrations do not elevate the angiogenic stimulus when applied during resistance exercise.
In: PLoS One. Bd. 8 (2013) Heft 11 . - e80143.
DOI: https://doi.org/10.1371/journal.pone.0080143

Suhr, Frank ; Bloch, Wilhelm:
Endothelial cell apoptosis : A new focal adhesion makes the difference.
In: Circulation Research. Bd. 111 (2012) Heft 12 . - S. 1488-1490.
DOI: https://doi.org/10.1161/CIRCRESAHA.112.278713

Gehlert, Sebastian ; Bungartz, Gerd ; Willkomm, Lena ; Korkmaz, Yüksel ; Pfannkuche, Kurt ; Schiffer, Thorsten ; Bloch, Wilhelm ; Suhr, Frank:
Intense resistance exercise induces early and transient increases in ryanodine receptor 1 phosphorylation in human skeletal muscle.
In: PLoS One. Bd. 7 (2012) Heft 11 . - e49326.
DOI: https://doi.org/10.1371/journal.pone.0049326

Suhr, Frank ; Brenig, Julian ; Müller, Rebecca ; Behrens, Hilke ; Bloch, Wilhelm ; Grau, Marijke:
Moderate exercise promotes human RBC-NOS activity, NO production and deformability through Akt kinase pathway.
In: PLoS One. Bd. 7 (2012) Heft 9 . - e45982.
DOI: https://doi.org/10.1371/journal.pone.0045982

Bloch, Wilhelm ; Suhr, Frank ; Zimmer, P.:
Molekulare Mechanismen der Herz- und Gefäßanpassung durch Sport : Einfluss von Epigenetik, Mechanotransduktion und freien Radikalen = Molecular mechanisms of exercise-induced cardiovascular adaptations : Influence of epigenetics, mechanotransduction and free radicals.
In: Herz. Bd. 37 (2012) Heft 5 . - S. 508-515.
DOI: https://doi.org/10.1007/s00059-012-3637-6

Xi, Jiaoya ; Khalil, Markus ; Shishechian, Nava ; Hannes, Tobias ; Pfannkuche, Kurt ; Liang, Huamin ; Fatima, Azra ; Haustein, Moritz ; Suhr, Frank ; Bloch, Wilhelm ; Reppel, Michael ; Šarić, Tomo ; Wernig, Marius ; Jänisch, Rudolf ; Brockmeier, Konrad ; Hescheler, Jürgen ; Pillekamp, Frank:
Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells.
In: The FASEB Journal. Bd. 24 (2010) Heft 8 . - S. 2739-2751.
DOI: https://doi.org/10.1096/fj.09-145177

Connes, Philippe ; Suhr, Frank ; Martin, Cyril ; Shin, Sehyun ; Aufradet, Emeline ; Sunoo, Sub ; Brixius, Klara ; de Mauverger, Eric Raynaud ; Romana, Marc ; Messonnier, Laurent ; Kang, Joonku ; Varlet-Marie, Emmanuelle ; Feasson, Leonard ; Hardy-Dessources, Marie-Dominique ; Bloch, Wilhelm ; Brun, Jean-Frederic:
New fundamental and applied mechanisms in exercise hemorheology.
In: Clinical Hemorheology and Microcirculation. Bd. 45 (2010) Heft 2-4 . - S. 131-141.
DOI: https://doi.org/10.3233/CH-2010-1291

Suhr, Frank ; Brixius, Klara ; Bloch, Wilhelm:
Angiogenic and vascular modulation by extracellular matrix cleavage products.
In: Current Pharmaceutical Design. Bd. 15 (2009) Heft 4 . - S. 389-410.
DOI: https://doi.org/10.2174/138161209787315756

Suhr, Frank ; Porten, Stefan ; Hertrich, Tim ; Brixius, Klara ; Schmidt, Annette ; Platen, Petra ; Bloch, Wilhelm:
Intensive exercise induces changes of endothelial nitric oxide synthase pattern in human erythrocytes.
In: Nitric Oxide. Bd. 20 (2009) Heft 2 . - S. 95-103.
DOI: https://doi.org/10.1016/j.niox.2008.10.004

Suhr, Frank ; Rosenwick, C. ; Vassiliadis, A. ; Bloch, Wilhelm ; Brixius, Klara:
Regulation of extracellular matrix compounds involved in angiogenic processes in short- and long-track elite runners.
In: Scandinavian Journal of Medicine & Science in Sports. Bd. 20 (2009) Heft 3 . - S. 441-448.
DOI: https://doi.org/10.1111/j.1600-0838.2009.00960.x

Suhr, Frank ; Brixius, Klara ; de Marées, Markus ; Bölck, Birgit ; Kleinöder, Heinz ; Achtzehn, Silvia ; Bloch, Wilhelm ; Mester, Joachim:
Effects of short-term vibration and hypoxia during high-intensity cycling exercise on circulating levels of angiogenic regulators in humans.
In: Journal of Applied Physiology. Bd. 103 (2007) Heft 2 . - S. 474-483.
DOI: https://doi.org/10.1152/japplphysiol.01160.2006