Zeitschrift: ChemMedChem

2024

You, Weijie ; Montoya, Alba L. ; Dana, Srikanta ; Franzini, Raphael M. ; Steegborn, Clemens:
Elucidating the Unconventional Binding Mode of a DNA‐Encoded Library Hit Provides a Blueprint for Sirtuin 6 Inhibitor Development.
In: ChemMedChem. (2024) . - e202400273.
ISSN 1860-7187
DOI: https://doi.org/10.1002/cmdc.202400273

2023

Khan, Tariq A. ; Al Nasr, Ibrahim S. ; Koko, Waleed S. ; Ma, Jingyi ; Eckert, Simon ; Brehm, Lucas ; Ben Said, Ridha ; Daoud, Ismail ; Hanachi, Riadh ; Rahali, Seyfeddine ; van de Sande, Wendy W. J. ; Ersfeld, Klaus ; Schobert, Rainer ; Biersack, Bernhard:
Evaluation of the Antiparasitic and Antifungal Activities of Synthetic Piperlongumine-Type Cinnamide Derivatives : Booster Effect by Halogen Substituents.
In: ChemMedChem. Bd. 18 (2023) Heft 12 . - e202300132.
ISSN 1860-7187
DOI: https://doi.org/10.1002/cmdc.202300132

2022

Köhler, Leonhard ; Reich, Sebastian ; Begemann, Gerrit ; Schobert, Rainer ; Biersack, Bernhard:
2-Amino-4-aryl-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitriles with Microtubule-Disruptive, Centrosome-Declustering, and Antiangiogenic Effects in vitro and in vivo.
In: ChemMedChem. Bd. 17 (2022) Heft 10 . - e202200064.
ISSN 1860-7187
DOI: https://doi.org/10.1002/cmdc.202200064

2015

di Fruscia, Paolo ; Zacharioudakis, Emmanouil ; Liu, Chang ; Moniot, Sébastien ; Laohasinnarong, Sasiwan ; Khongkow, Mattaka ; Harrison, Ian F. ; Koltsida, Konstantina ; Reynolds, Christopher R. ; Schmidtkunz, Karin ; Jung, Manfred ; Chapman, Kathryn L. ; Steegborn, Clemens ; Dexter, David T. ; Sternberg, Michael J. E. ; Lam, Eric W.-F. ; Fuchter, Matthew J.:
The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model.
In: ChemMedChem. Bd. 10 (2015) Heft 1 . - S. 69-82.
ISSN 1860-7187
DOI: https://doi.org/10.1002/cmdc.201402431

2008

Hahn, Frank ; Schmitz, Katja ; Balaban, Theodor S. ; Bräse, Stefan:
Conjugation of Spermine Facilitates Cellular Uptake and Enhances Antitumor and Antibiotic Properties of Highly Lipophilic Porphyrins.
In: ChemMedChem. Bd. 3 (2008) Heft 8 . - S. 1185-1188.
ISSN 1860-7187
DOI: https://doi.org/10.1002/cmdc.200800013