Publications "Köhler, Leonhard"

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Number of items: 9.

Article in a journal

Schleser, Sebastian W. ; Köhler, Leonhard ; Riethmüller, Florian ; Reich, Sebastian ; Fertig, Robin ; Schlotte, Luca ; Seib, Jonathan ; Goller, Alexander ; Begemann, Gerrit ; Kempe, Rhett ; Schobert, Rainer:
Anti-Tumoural NHC(thiolato) Gold(I) Complexes Derived from HIF-1α Inhibitor AC1-004 Target the Mitochondrial Redox System and Show Antiangiogenic Effects in vivo.
In: ChemPlusChem. Vol. 88 (2023) Issue 5 . - e202300167.
ISSN 2192-6506
DOI: https://doi.org/10.1002/cplu.202300167

Köhler, Leonhard ; Reich, Sebastian ; Yusenko, Maria ; Klempnauer, Karl-Heinz ; Begemann, Gerrit ; Schobert, Rainer ; Biersack, Bernhard:
Multimodal 4-arylchromene derivatives with microtubule-destabilizing, anti-angiogenic, and MYB-inhibitory activities.
In: Cancer Drug Resistance. Vol. 6 (2023) . - pp. 59-77.
ISSN 2578-532X
DOI: https://doi.org/10.20517/cdr.2022.90

Abouelhaoul, El Alami ; El Kihel, Abdellatif ; Ahbala, Mustapha ; Sdassi, Hamid ; Köhler, Leonhard ; Bauchat, Patrick ; Roisnel, Thierry ; Khan, Tariq A. ; Al Nasr, Ibrahim S. ; Koko, Waleed S. ; Schobert, Rainer ; Biersack, Bernhard:
Regiospecific Reduction of 4,6-Dinitrobenzimidazoles : Synthesis, Characterization, and Biological Evaluation.
In: Chemistry & Biodiversity. Vol. 20 (2023) Issue 7 . - e202300191.
ISSN 1612-1880
DOI: https://doi.org/10.1002/cbdv.202300191

Köhler, Leonhard ; Reich, Sebastian ; Begemann, Gerrit ; Schobert, Rainer ; Biersack, Bernhard:
2-Amino-4-aryl-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitriles with Microtubule-Disruptive, Centrosome-Declustering, and Antiangiogenic Effects in vitro and in vivo.
In: ChemMedChem. Vol. 17 (2022) Issue 10 . - e202200064.
ISSN 1860-7187
DOI: https://doi.org/10.1002/cmdc.202200064

Köhler, Leonhard ; Reich, Sebastian ; Yusenko, Maria ; Klempnauer, Karl-Heinz ; Shaikh, Amin H. ; Ahmed, Khursheed ; Begemann, Gerrit ; Schobert, Rainer ; Biersack, Bernhard:
A New Naphthopyran Derivative Combines c-Myb Inhibition, Microtubule-Targeting Effects, and Antiangiogenic Properties.
In: ACS Medicinal Chemistry Letters. Vol. 13 (2022) Issue 11 . - pp. 1783-1790.
ISSN 1948-5875
DOI: https://doi.org/10.1021/acsmedchemlett.2c00403

Bär, Sofia I. ; Gold, Madeleine ; Schleser, Sebastian W. ; Rehm, Tobias ; Bär, Alexander ; Köhler, Leonhard ; Carnell, Lucas R. ; Biersack, Bernhard ; Schobert, Rainer:
Guided Antitumoural Drugs : (Imidazol-2-ylidene)(L)gold(I) Complexes Seeking Cellular Targets Controlled by the Nature of Ligand L.
In: Chemistry : a European Journal. Vol. 27 (2021) Issue 15 . - pp. 5003-5010.
ISSN 1521-3765
DOI: https://doi.org/10.1002/chem.202005451

Rothemund, Matthias ; Bär, Alexander ; Klatt, Felix ; Weidler, Sascha ; Köhler, Leonhard ; Unverzagt, Carlo ; Kuhn, Claus-D. ; Schobert, Rainer:
N-Metallocenoylsphingosines as targeted ceramidase inhibitors : Syntheses and antitumoral effects.
In: Bioorganic Chemistry. Vol. 97 (2020) . - 103703.
ISSN 0045-2068
DOI: https://doi.org/10.1016/j.bioorg.2020.103703

Gold, Madeleine ; Köhler, Leonhard ; Lanzloth, Clarissa ; Andronache, Ion ; Anant, Shrikant ; Dandawate, Prasad ; Biersack, Bernhard ; Schobert, Rainer:
Synthesis and bioevaluation of new vascular-targeting and anti-angiogenic thieno[2,3-d]pyrimidin-4(3H)-ones.
In: European Journal of Medicinal Chemistry. Vol. 189 (2020) . - 112060.
ISSN 0223-5234
DOI: https://doi.org/10.1016/j.ejmech.2020.112060

Doctoral thesis

Köhler, Leonhard:
Biochemische Evaluation und strukturelle Optimierung von Naphtopyran-Derivaten mit Mikrotubuli-destabilisierenden, antiangiogenen und c-MYB-inhibierenden Eigenschaften.
Bayreuth , 2023 . - 171, XIII p.
( Doctoral thesis, 2023 , Universität Bayreuth, Fakultät für Biologie, Chemie und Geowissenschaften)
DOI: https://doi.org/10.15495/EPub_UBT_00007343

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