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Die Kontrolle zyklischer Nukleotide mittels Licht

Title data

Stabel, Robert ; Möglich, Andreas:
Die Kontrolle zyklischer Nukleotide mittels Licht.
In: BIOspektrum. Vol. 23 (2017) Issue 4 . - pp. 384-387.
ISSN 1868-6249
DOI: https://doi.org/10.1007/s12268-017-0813-5

Abstract in another language

Sensory photoreceptors underpin diverse adaptive responses in nature and serve as genetically encoded, light-gated actuators in optogenetics. Photoactivated nucleotide cyclases (PACs) enable light-dependent control over the formation of cyclic nucleotides (cNMPs). Conversely, the engineered, red-light-activated phosphodiesterase LAPD mediates the hydrolytic breakdown of cNMPs. In combination, PACs and LAPD hence unlock precise and graded control over intracellular cNMPs and associated processes.

Further data

Item Type: Article in a journal
Refereed: No
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry > Chair Biochemistry - Univ.-Prof. Dr. Andreas Möglich
Faculties
Faculties > Faculty of Biology, Chemistry and Earth Sciences
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry
Result of work at the UBT: Yes
DDC Subjects: 500 Science > 570 Life sciences, biology
Date Deposited: 28 Jun 2017 06:54
Last Modified: 28 Jun 2017 06:54
URI: https://eref.uni-bayreuth.de/id/eprint/38201