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Performance of the Intermittently Scanned Continuous Glucose Monitoring (isCGM) System during a High Oral Glucose Challenge in Adults with Type 1 Diabetes : A Prospective Secondary Outcome Analysis

Title data

Moser, Othmar ; Tripolt, Norbert ; Pferschy, Peter ; Obermayer, Anna ; Kojzar, Harald ; Müller, Alexander ; Yildirim, Hakan ; Sourij, Caren ; Eckstein, Max L. ; Sourij, Harald:
Performance of the Intermittently Scanned Continuous Glucose Monitoring (isCGM) System during a High Oral Glucose Challenge in Adults with Type 1 Diabetes : A Prospective Secondary Outcome Analysis.
In: Biosensors. Vol. 11 (January 2021) Issue 1 .
ISSN 2079-6374
DOI: https://doi.org/10.3390/bios11010022

Abstract in another language

To assess intermittently scanned continuous glucose monitoring (isCGM) performance for different rates of change in plasma glucose (RCPG) during glycemic challenges in type 1 diabetes (T1D). Nineteen people with T1D (7 females; age 35 ± 11 years; HbA1c 7.3 ± 0.6% (56 ± 7 mmol/mol)) performing two glycemic challenges (OGTT) were included. During OGTTs, plasma glucose was compared against sensor glucose for timepoints 0 min (pre‐OGTT), +15 min, +30 min, +60 min, +120 min, +180 min, and +240 min by means of median absolute (relative) difference (MARD and MAD) and Clarke Error Grid (CEG), then was stratified for RCPG and glycemic ranges. Overall, MARD was 8.3% (4.0–14.8) during hypoglycemia level 1 18.8% (15.8–22.0), euglycemia 9.5% (4.3–15.1), hy‐perglycemia level 1 9.4% (4.0–17.2), and hyperglycemia level 2 7.1% (3.3–11.9). The MARD was as‐sociated with the RCPG (p < 0.0001), detailing significant differences in comparison of low, moderate, high, and very high RCPG (p = 0.014). Overall, CEG resulted in 88% (212 values) of comparison points in zone A, 12% (29 values) in zone B, and 0.4% (1 value) in zone D. The isCGM system was accurate during OGTTs. Its performance was dependent on the RCPG and showed an overestimation of the actual reference glucose during hypoglycemia.

(PDF) Performance of the Intermittently Scanned Continuous Glucose Monitoring (isCGM) System during a High Oral Glucose Challenge in Adults with Type 1 Diabetes- A Prospective Secondary Outcome Analysis. Available from: https://www.researchgate.net/publication/348521264_Performance_of_the_Intermittently_Scanned_Continuous_Glucose_Monitoring_isCGM_System_during_a_High_Oral_Glucose_Challenge_in_Adults_with_Type_1_Diabetes-_A_Prospective_Secondary_Outcome_Analysis [accessed May 07 2021].

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: sCGM; glycemia; accuracy
Institutions of the University: Faculties > Faculty of Cultural Studies > Department of Sport Science > Chair Exercise Physiology > Chair Exercise Physiology - Univ.-Prof. Dr. Othmar Moser
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences > 610 Medicine and health
Date Deposited: 31 May 2021 07:36
Last Modified: 31 May 2021 07:39
URI: https://eref.uni-bayreuth.de/id/eprint/65132