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A comparison of associations with childhood lung function between air pollution exposure assessment methods with and without accounting for time-activity patterns

Title data

Ntarladima, Anna-Maria ; Karssenberg, Derek ; Vaartjes, Ilonca ; Grobbee, Diederick E ; Schmitz, Oliver ; Lu, Meng ; Boer, Jolanda ; Koppelman, Gerard ; Vonk, Judith ; Vermeulen, Roel:
A comparison of associations with childhood lung function between air pollution exposure assessment methods with and without accounting for time-activity patterns.
In: Environmental Research Letters. Vol. 202 (November 2021) . - No. 111710.
ISSN 1748-9326
DOI: https://doi.org/10.1016/j.envres.2021.111710

Abstract in another language

Background: To investigate associations between annual average air pollution exposures and health, most epidemiological studies rely on estimated residential exposures because information on actual time-activity patterns can only be collected for small populations and short periods of time due to costs and logistic constraints. In the current study, we aim to compare exposure assessment methodologies that use data on time-activity patterns of children with residence-based exposure assessment. We compare estimated exposures and associations with lung function for residential exposures and exposures accounting for time activity patterns.
Methods: We compared four annual average air pollution exposure assessment methodologies; two rely on residential exposures only, the other two incorporate estimated time activity patterns. The time-activity patterns were based on assumptions about the activity space and make use of available external data sources for the duration of each activity. Mapping of multiple air pollutants (NO2, NOX, PM2.5, PM2.5absorbance, PM10) at a fine resolution as input to exposure assessment was based on land use regression modelling. First, we assessed the correlations between the exposures from the four exposure methods. Second, we compared estimates of the cross-sectional associations between air pollution exposures and lung function at age 8 within the PIAMA birth cohort study for the four exposure assessment methodologies.
Results: The exposures derived from the four exposure assessment methodologies were highly correlated (R > 0.95) for all air pollutants. Similar statistically significant decreases in lung function were found for all four methods. For example, for NO2 the decrease in FEV1 was -1.40% (CI; -2.54, -0.24%) per IQR (9.14 μg/m3) for front door exposure, and -1.50% (CI; -2.68, -0.30%) for the methodology which incorporates time activity pattern and actual school addresses.
Conclusions: Exposure estimates from methods based on the residential location only and methods including time activity patterns were highly correlated and associated with similar decreases in lung function. Our study illustrates that the annual average exposure to air pollution for 8-year-old children in the Netherlands is sufficiently captured by residential exposures.

Further data

Item Type: Article in a journal
Refereed: Yes
Keywords: Air pollution; Exposure assessment; Lung function; Activity patterns
Institutions of the University: Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Earth Sciences > Juniorprofessur Geoinformatik - Spatial Big Data
Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Earth Sciences > Juniorprofessur Geoinformatik - Spatial Big Data > Juniorprofessur Geoinformatik - Spatial Big Data - Juniorprof. Dr. Meng Lu
Result of work at the UBT: Yes
DDC Subjects: 000 Computer Science, information, general works
300 Social sciences > 310 Statistics
500 Science > 550 Earth sciences, geology
Date Deposited: 02 Dec 2021 08:45
Last Modified: 02 Dec 2021 08:45
URI: https://eref.uni-bayreuth.de/id/eprint/68058