A more complete picture of metal hyperaccumulation through next-generation sequencing technologies

Title data

Verbruggen, Nathalie ; Hanikenne, Marc ; Clemens, Stephan:
A more complete picture of metal hyperaccumulation through next-generation sequencing technologies.
In: Frontiers in Plant Science. Vol. 4 (2013) . - 388.
ISSN 1664-462X
DOI: https://doi.org/10.3389/fpls.2013.00388

Official URL:

Abstract in another language

The mechanistic understanding of metal hyperaccumulation has benefitted immensely from the use of molecular genetics tools developed for Arabidopsis thaliana. The revolution in DNA sequencing will enable even greater strides in the near future, this time not restricted to the family Brassicaceae. Reference genomes are within reach for many ecologically interesting species including heterozygous outbreeders. They will allow deep RNA-seq transcriptome studies and the re-sequencing of contrasting individuals to unravel the genetic basis of phenotypic variation. Cell-type specific transcriptome analyses, which will be essential for the dissection of metal translocation pathways in hyperaccumulators, can be achieved through the combination of RNA-seq and translatome approaches. Affordable high-resolution genotyping of many individuals enables the elucidation of quantitative trait loci in intra- and interspecific crosses as well as through genome-wide association mapping across large panels of accessions. Furthermore, genome-wide scans have the power to detect loci under recent selection. Together these approaches will lead to a detailed understanding of the evolutionary path towards the emergence of hyperaccumulation traits.

Further data

Item Type:	Article in a journal
Refereed:	Yes
Additional notes:	BAYCEER117974
Institutions of the University:	Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Plant Physiology Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Biology > Chair Plant Physiology > Chair Plant Physiology - Univ.-Prof. Dr. Stephan Clemens Research Institutions Research Institutions > Central research institutes Research Institutions > Central research institutes > Bayreuth Center of Ecology and Environmental Research- BayCEER
Result of work at the UBT:	No
DDC Subjects:	500 Science 500 Science > 570 Life sciences, biology 500 Science > 580 Plants (Botany)
Date Deposited:	24 Apr 2015 11:56
Last Modified:	14 Jun 2023 13:27
URI:	https://eref.uni-bayreuth.de/id/eprint/11417