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Acute, Low-dose CO Inhalation does not Alter Energy Expenditure during Submaximal Exercise

Title data

Kane, L. A. ; Ryan, Benjamin J. ; Schmidt, Walter ; Byrnes, William C.:
Acute, Low-dose CO Inhalation does not Alter Energy Expenditure during Submaximal Exercise.
In: International Journal of Sports Medicine. Vol. 37 (2016) Issue 1 . - pp. 19-24.
ISSN 1439-3964
DOI: https://doi.org/10.1055/s-0035-1554641

Abstract in another language

Carbon monoxide, a gas known most widely for its toxic effects at high doses, is receiving increased attention for its role as a physiological signaling molecule and potential therapeutic agent when administered in low doses. We sought to quantify any changes to oxygen consumption and energy expenditure during submaximal exercise after low-dose CO inhalation. 9 active individuals completed 4 graded submaximal exercise tests, with each test occurring during a separate visit. For their first exercise test, subjects inhaled CO or room air (1.2 mL·kg(-1) body mass) in a randomized, subject-blind fashion. A second test was repeated 24 h later when the inhaled gas should have cleared the system. Subjects repeated study procedures with the alternate dose after a washout period of at least 2 days. Low-dose CO administration did not affect oxygen consumption or energy expenditure during submaximal exercise immediately or 24 h following its administration. Increases in heart rate, blood [lactate], and perceived exertion were observed following acute CO inhalation but these effects were absent after 24 h. The results of this study suggest that low-dose CO administration does not influence the energetics of submaximal exercise, but it acutely increases the relative intensity associated with absolute workloads below the lactate threshold.

Further data

Item Type: Article in a journal
Refereed: Yes
Institutions of the University: Faculties > Faculty of Cultural Studies > Department of Sport Science
Faculties > Faculty of Cultural Studies > Department of Sport Science > Professor Sport Science IV - Sports Medicine and Sports Physiology
Faculties
Faculties > Faculty of Cultural Studies
Result of work at the UBT: Yes
DDC Subjects: 600 Technology, medicine, applied sciences > 610 Medicine and health
Date Deposited: 07 Sep 2017 11:45
Last Modified: 15 Sep 2022 09:31
URI: https://eref.uni-bayreuth.de/id/eprint/39240