Title data
Jin, Xilang ; Wu, Shaoping ; She, Mengyao ; Jia, Yifan ; Hao, Likai ; Yin, Bing ; Wang, Lanying ; Obst, Martin ; Shen, Yehua ; Zhang, Yongmin ; Li, Jianli:
Novel Fluorescein-Based Fluorescent Probe for Detecting H2S and Its Real Applications in Blood Plasma and Biological Imaging.
In: Analytical Chemistry.
Vol. 88
(2016)
Issue 22
.
- pp. 11253-11260.
ISSN 1520-6882
DOI: https://doi.org/10.1021/acs.analchem.6b04087
Abstract in another language
A broad-spectrum fluorescent probe, which can be applied to monitoring H2S in various biological systems, has been rationally designed and synthesized. This specific probe was applied to localize the endogenous H2S in living Raw264.7 macrophage cells, HepG2 cells, and H9C2 cells. At the same time, the probe has successfully visualized CBS- and CSE- induced endogenous H2S production and monitored CBS and CSE activity in H9C2 cells. This probe could serve as a powerful molecular imaging tool to further explore the physiological function and the molecular mechanisms of endogenous H2S in living animal systems.
Further data
Item Type: | Article in a journal |
---|---|
Refereed: | Yes |
Additional notes: | BAYCEER140410 |
Institutions of the University: | Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Earth Sciences > Heisenberg Professorship - Experimental Biogeochemistry > Heisenberg Professorship - Experimental Biogeochemistry - Univ.-Prof. Dr. Martin Obst Research Institutions Research Institutions > Research Centres Research Institutions > Research Centres > Bayreuth Center of Ecology and Environmental Research- BayCEER Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Earth Sciences > Heisenberg Professorship - Experimental Biogeochemistry |
Result of work at the UBT: | Yes |
DDC Subjects: | 500 Science |
Date Deposited: | 12 Jan 2018 08:31 |
Last Modified: | 15 Sep 2020 08:53 |
URI: | https://eref.uni-bayreuth.de/id/eprint/41298 |