Title data
Sticht, Heinrich ; Bayer, Peter ; Willbold, Dieter ; Dames, Sonja ; Hilbich, Caroline ; Beyreuther, Konrad ; Frank, Rainer W. ; Rösch, Paul:
Structure of Amyloid A4-(1-40)-Peptide of Alzheimer's Disease.
In: European Journal of Biochemistry.
Vol. 233
(1995)
Issue 1
.
- pp. 293-298.
ISSN 1432-1033
DOI: https://doi.org/10.1111/j.1432-1033.1995.293_1.x
Abstract in another language
One of the principal peptide components of the amyloid plaque deposits of Alzheimer's disease in humans is the 40-amino-acid peptide 8-amyloid A4-(1-40)-peptide. The full-length A4-(I-40)-peptide was chemically synthesized and the sulution structure determined by two-dimensional nuclear magnetic resonance spectroscopy and restrained molecular-dynamics calculations. Synthetic human A4-(1-40)-peptide was soluble and non-aggregating for several days in 40% (by vol.) trifluoroethanol/water. All spin systems could ...
Further data
Item Type: | Article in a journal |
---|---|
Refereed: | Yes |
Institutions of the University: | Faculties Faculties > Faculty of Biology, Chemistry and Earth Sciences Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry with an Emphasis on Biophysical Chemistry Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors > Chair Biopolymers - Univ.-Prof. Dr. Paul Rösch Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Former Professors |
Result of work at the UBT: | Yes |
DDC Subjects: | 500 Science > 500 Natural sciences 500 Science > 540 Chemistry 500 Science > 570 Life sciences, biology |
Date Deposited: | 19 Dec 2014 09:38 |
Last Modified: | 31 Mar 2022 13:25 |
URI: | https://eref.uni-bayreuth.de/id/eprint/5082 |